Objective To study the value of ultrasound-guided fine needle aspiration biopsy (FNAB) in diagnosing TI-RADS 4 thyroid nodules. Methods A retrospective analysis was conducted on the data of 217 patients with 221 thyroid nodules of TI-RADS 4 by ultrasound-guided FNAB. The cases were divided into TI-RADS 4A group, TI-RADS 4B group and TI-RADS 4C group. Postoperative pathological results were taken as gold standard and Kappa consistency test was used to evaluate the consistency of ultrasound-guided FNAB with postoperative pathological results. The specificity, sensitivity, negative and positive predictive values of ultrasound-guided FNAB were gotten based on postoperative pathological results as standard. Results The Kappa values were 0.86 of TI-RADS 4A group, 0.77 of TI-RADS 4B group and 0.82 of TI-RADS 4C group, respectively. All values were more than 0.75. Specificity, sensitivity, negative and positive predictive values of ultrasound-guided FNAB were 98.1%, 77.8%, 96.2%, 88.0% in TI-RADS 4A group; 90.6%, 86.0%, 88.9%,88.1% in TI-RADS 4B group; and 83.3%, 98.3%, 83.3%, 98.3% in TI-RADS 4C group. Higher consistence was seen between with postoperative pathological results and ultrasound-guided FNAB results (P<0.01). Conclusions Combination of TI-RADS classification and ultrasound-guided FNAB can increase the accuracy of ultrasound diagnosis of TI-RADS 4 thyroid nodules.
TAN Xingli, PENG Shiyi, ZHOU Zhiying
. Ultrasound-guided fine needle aspiration biopsy for TI-RADS 4 thyroid nodules[J]. Journal of Surgery Concepts & Practice, 2019
, 24(01)
: 75
-78
.
DOI: 10.16139/j.1007-9610.2019.01.016
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