Objective To investigate diffusion-weighted magnetic resonance imaging (DWI) using free-breathing with fat suppression acquisitions for the differential diagnosis of autoimmune pancreatitis (AIP) from pancreatic cancer. Methods The retrospective study was performed with both 15 cases of AIP and 30 cases of pancreatic cancer diagnosed by pathology. All patients underwent T1WI, T2WI, MRCP and DWI preoperatively on 3.0T MR imaging. Based on SE-EPI sequence using b values of 0 and 600 s/mm2, DWI sequences using free-breathing with fat suppression acquisitions were done. Apparent diffusion coefficient (ADC) value was obtained for the patients in AIP group and pancreatic cancer group. Results There was no statistical difference in sex, locus of lesion, upper abdomen pain, and jaundice of patients between 2 groups (P>; 0.05). Both AIP and pancreatic cancer displayed high signal intensity on images of DWI sequences using free-breathing acquisitions. DWI excellent rate was 95.5%. ADC value of AIP and pancreatic cancer was (0.001 58± 0.000 21) mm2/s and (0.001 87± 0.000 29) mm2/s respectively, with statistical difference between 2 groups (P=0.001 6). Conclusion DWI using free-breathing with fat suppression acquisitions may be helpful in differential diagnosis of AIP from pancreatic cancer.
YAN Cheng, NI Xiaoyan, YAO Xiuzhong, CHEN Caizhong, GU Junying
. Diagnostic value of free-breath diffusion-weighted MR imaging in autoimmune pancreatitis and pancreatic cancer[J]. Journal of Surgery Concepts & Practice, 2019
, 24(03)
: 230
-235
.
DOI: 10.16139/j.1007-9610.2019.03.012
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