Journal of Surgery Concepts & Practice >

2021 , Vol. 26 >Issue 06: 528 - 531

DOI: https://doi.org/10.16139/j.1007-9610.2021.06.014

Original article

Clinicopathological analysis of papillary thyroid microcarcinoma in isthmus

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  • 1a. Department of Ultrasonography, 1b. Department of General Surgery, Luwan Branch of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China
    2. Department of Ultrasonography, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2021-06-09

  Online published: 2022-07-27

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Abstract

Objective To evaluate the clinicopathological characteristics of papillary thyroid microcarcinoma (PTMC) located in the isthmus. Methods The clinical and pathological data of 477 cases with PTMC diagnosed pathologically were retrospectively analyzed. Differences in PTMC between isthmus and lateral lobe were compared. Results Multivariate analysis showed that there were significantly difference in cancer capsule contact (30.5% vs. 10.4%, P=0.001) and lymph node metastasis (LNM) (42.7% vs. 18.7%, P<0.001) of PTMC between isthmus and lateral lobe. When compared with PTMC in lateral lobe, PTMC in isthmus was more prone to in ipsilateral central LNM (41.5% vs. 17.5%, P<0.001), ipsilateral lateral LNM (8.5% vs. 2.8%, P=0.022) and bilateral central LNM (12.2% vs. 0.2%, P<0.001), and contralateral lateral LNM (3.7% vs. 0, P<0.001). Conclusions PTMC in isthmus had capsular contact and LNM with higher proportion compared with PTMC in lateral lobe. It should suggest bilateral central lymph node dissection for PTMC located in isthmus.

Key words： Isthmus; Papillary thyroid microcarcinoma; Clinicopathological feature; Lymph node metastasis; Central group

Cite this article

FAN Jinfang, SHEN Yi, ZHAN Weiwei, TAO Lingling, LI Weiwei, KUANG Lijun, ZHOU Wei . Clinicopathological analysis of papillary thyroid microcarcinoma in isthmus[J]. Journal of Surgery Concepts & Practice, 2021 , 26(06) : 528 -531 . DOI: 10.16139/j.1007-9610.2021.06.014

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