Journal of Surgery Concepts & Practice >

2025 , Vol. 30 >Issue 05: 378 - 384

DOI: https://doi.org/10.16139/j.1007-9610.2025.05.02

Experts forum

Advances in endoscopic ultrasound-guided celiac plexus neurolysis and its derivative techniques

  • AO Xinyi ,
  • LI Li ,
  • LI Zhi ,
  • WANG Kaixuan
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  • 1. Department of Spleen and Stomach Diseases, the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Sichuan Luzhou 646000, China
    2. Department of Gastroenterology, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
    3. North Sichuan Medical College School of Clinical Integrated Traditional Chinese and Western Medicine，Sichuan Nanchong 637100，China

Received date: 2025-06-20

  Online published: 2025-12-09

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Abstract

This review systematically summarizes the clinical applications and recent advances of endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) and its derived techniques. It addressed the indications, contraindications, technical challenges, and procedural principles, with a detailed overview of unilateral and bilateral injection, EUS-guided celiac ganglia neurolysis (EUS-CGN), EUS-guided broad-plexus neurolysis (EUS-BPN), as well as radiofrequency ablation and radioactive seed implantation. In addition, complications and their preventive strategies were discussed, and future directions were highlighted, aiming to provide technical references and decision-making guidance for clinical practice.

Key words： Endoscopic ultrasound (EUS); Celiac plexus neurolysis (CPN); Cancer pain; Ganglion injection; Radiofrequency ablation (RFA)

Cite this article

AO Xinyi , LI Li , LI Zhi , WANG Kaixuan . Advances in endoscopic ultrasound-guided celiac plexus neurolysis and its derivative techniques[J]. Journal of Surgery Concepts & Practice, 2025 , 30(05) : 378 -384 . DOI: 10.16139/j.1007-9610.2025.05.02

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