Journal of Surgery Concepts & Practice >

2025 , Vol. 30 >Issue 05: 438 - 443

DOI: https://doi.org/10.16139/j.1007-9610.2025.05.10

Case report

Comprehensive diagnosis and treatment strategy for functional pancreas neuroendocrine neoplasm： a report of 3 cases

  • JI Bei ,
  • SHANG Zhengye ,
  • TUO Biguang ,
  • LIU Xuemei
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  • Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Guizhou Zunyi 563000, China

Received date: 2025-06-29

  Online published: 2025-12-09

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Abstract

Functional neuroendocrine neoplasm, which secrete hormones and lead to diverse clinical symptoms, pose significant challenges in diagnosis and treatment. Early identification and standardized management are crucial for improving patient prognosis. This article summarized three clinically relatively common cases of Functional pancreatic neuroendocrine neoplasm (F-pNENs), focusing on analyzing their diagnostic key points and standardized therapeutic pathways. It aimed to provide reference for early clinical identification of rare tumors and improvement of standardized multidisciplinary diagnosis and treatment as well as personalized treatment strategies.

Key words： Neuroendocrine neoplasm; Functional pancreatic neuroendocrine neoplasm (F-pNEN); Glucagonoma; Insulinoma; Vasoactive intestinal peptide tumor (VIPoma)

Cite this article

JI Bei , SHANG Zhengye , TUO Biguang , LIU Xuemei . Comprehensive diagnosis and treatment strategy for functional pancreas neuroendocrine neoplasm： a report of 3 cases[J]. Journal of Surgery Concepts & Practice, 2025 , 30(05) : 438 -443 . DOI: 10.16139/j.1007-9610.2025.05.10

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