组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2017, Vol. 13 ›› Issue (4): 228-231.doi: 10.3969/j.issn.1673-0364.2017.04.014

• 综述 • 上一篇    下一篇

Ⅱ型胶原水凝胶在软骨损伤修复中的研究进展

梁仟，朱飞燕，黄江鸿，王大平，熊建义   

  1. 汕头大学医学院；深圳市第二人民医院国家重点骨科；深圳市组织工程重点实验室；深圳市数字骨科技术工程实验室
  • 发布日期:2020-07-23

Research Progress of Type H Collagen Hydrogel in Cartilage Injury

LIANG Qian,ZHU Feiyan,HUANG Jianghong,WANG Daping,XIONG Jianyi   

  1. Shantou University Medical College;Shenzhen Second People’s Hospital
  • Published:2020-07-23
  • Contact: 广东省科技计划项目(2017A020215116)；广东省医学科研基金项目(A2017189)；深圳市科技计划项目(JCYJ20170306092315034)；深圳市科创委基础布局项目(JCYJ20160301111338144)

摘要： 作为一类新型的天然细胞支架,Ⅱ型胶原水凝胶具有良好的生物特性和理化性质,对软骨损伤修复具有很大的研究意义和临床应用价值。本文综述了近年来国内外Ⅱ型胶原水凝胶在软骨损伤修复中的研究进展,为软骨组织工程细胞支架的选择提供参考。

关键词: Ⅱ型胶原, 水凝胶, 支架材料, 种子细胞, 软骨, 组织工程

Abstract: As a new type of natural cell scaffold,type Ⅱ collagen hydrogel with good biocompatibility and physicochemical properties has great significance and clinical application value for the repair of cartilage injury.In this paper,the recent advances of type Ⅱ collagen hydrogel in the repair of cartilage injury at home and abroad were reviewed,so as to provide a reference for the selection of cell scaffolds for cartilage tissue engineering.

Key words: Type Ⅱ collagen, Hydrogel, Scaffold materials, Seed cell, Cartilage, Tissue engineering

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