组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2016, Vol. 12 ›› Issue (5): 319-321.doi: 10.3969/j.issn.1673-0364.a459

• 综述 • 上一篇    下一篇

骨组织工程的研究进展和面临的问题

周晓，盛小伍，曾勇   

  1. 湖南省肿瘤医院
  • 发布日期:2020-07-23

The Research Progress and L im itations of Bone Tissue Engineering

ZHOU Xiao,SHENG Xiaowu,ZENG Yong   

  1. Hunan Cancer Hospital,Changsha 410013,China.Corresponding author:ZHOU Xiao E-mail:cccdon@sina.com).
  • Published:2020-07-23
  • Contact: 国家卫生计生委临床重点专科（肿瘤科）建设项目子项目。

摘要： 骨缺损修复的移植物按其来源,可分为自体骨、同种异体骨、异种骨等,均存在自身的局限性。组织工程技术有望产生和人体骨类似的骨组织,解决目前骨缺损治疗的局限性。我们针对骨组织工程,就其临床研究进展以及亟待解决的问题进行综述。

关键词: 组织工程, 生长因子, 支架, 细胞外基质

Abstract: The graft for repairing bone grafts can be categorized as autografts, allografts, and xenografts. However, each type of donor tissue comes with its own set of limitations. Tissue engineering strategies have been applied as promising alternatives to produce bone constructs that mimic the structure of natural bone and solve the limitations of bone defect treatment. In this paper, the research progress of bone tissue engineering was reviewed, and the limitations of current bone tissue approaches were discussed.

Key words: Tissue engineering, Growth factor, Scaffolds, Extracellularmatrix

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