组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (3): 277-.

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高海拔地区右美托咪定复合丙泊酚联合瑞芬太尼在头面部整形美容手术中的麻醉效果探究

  

  • 出版日期:2025-06-02 发布日期:2025-07-01

Anesthetic effect of dexmedetomidine combined with propofol and remifentanil in head and face plastic surgery in plateau area

  • Online:2025-06-02 Published:2025-07-01

摘要: 目的 探讨右美托咪定复合丙泊酚联合瑞芬太尼在高海拔地区实施头面部整形美容手术的麻醉效果。方 法 本研究纳入西藏地区 3 600米海拔某三甲医院 2023年 3月至 2024年 12月收治的 32例头面部整形美容患者,采用 右美托咪定复合丙泊酚联合瑞芬太尼麻醉。结果 32例患者术中血流动力学稳定,循环波动小,术后镇痛镇静效果好, 术后不良反应总发生率为 12.5%。结论 右美托咪定复合丙泊酚联合瑞芬太尼的麻醉方案在高海拔地区具有显著优 势,在血流动力学稳定性方面可有效抑制插管及手术刺激引发的应激反应。

关键词: 右美托咪定, &emsp, 丙泊酚, &emsp, 瑞芬太尼, &emsp, 整形美容手术, &emsp, 高海拔地区

Abstract: Objective To investigate the anesthetic effect of dexmedetomidine combined with propofol and remifentanil in head and face plastic surgery in plateau area. Methods A total of 32 head and facial plastic surgery patients were enrolled in a Grade-III hospital at an altitude of 3,600 meters in Tibet Autonomous Region from March 2023 to December 2024. Patients were anesthetised with dexmedetomidine combined with propofol and remifentanil. Results  All 32 patients had stable hemodynamics, little circulation fluctuation, good postoperative analgesia and sedation, and the total incidence of postoperative adverse reactions was 12.5%. Conclusion  The anesthesia regimen of dexmedetomidine combined with propofol and remifentanil has significant advantages in the plateau area, and can effectively inhibit the stress response caused by intubation and surgical stimulation in terms of hemodynamic stability.

Key words: Dexmedetomidine, &emsp, Propofol, &emsp, Remifentanil, &emsp, Plastic surgery, &emsp, Plateau area