Effect of Botulinum Toxin Type A on the Expression of Substance P, Calcitionin Gene-Related Peptide, TGF-β1 and α-Smooth Muscle Actin a in Wound Healing in Rats

doi:10.3969/j.issn.1673-0364.2009.08.006

Abstract

Abstract: Objective To investigate the effect of botulinum toxin type A on the expression of substance P and calcitionin gene-related peptide in wound healing. Methods Forty rats were randomly divided into Group C (Control) and Group E (Experimental), 20 rats in each group. The wound-healing model was established by excised four full-thickness skin (1 cm × 1 cm, circled the injection site) in the back of all SD rats 7 days after BTA injection. The area of wound was measured and calculated at the 3rd d and 7th day aft...

Key words: Botulinum toxin type A, Substance P, Calcitionin gene-related peptide, Wound healing, Scar

CLC Number:

R619+.6

WANG Lin,TAI Ningzheng,CHEN Rui,FAN Zhihong. Effect of Botulinum Toxin Type A on the Expression of Substance P, Calcitionin Gene-Related Peptide, TGF-β1 and α-Smooth Muscle Actin a in Wound Healing in Rats[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(4): 202-228.

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Effect of Botulinum Toxin Type A on the Expression of Substance P, Calcitionin Gene-Related Peptide, TGF-β1 and α-Smooth Muscle Actin a in Wound Healing in Rats

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