Abstract: Objectives To evaluate endovascular therapy for venous malformations and its safety and efficacy of the treatment.Methods Six hundred and twenty eight sclerotherapy sessions were performed on 211 patients,aged 2-54 years(mean,14.5 years).There were 104 females and 107 males.All patients had a pre-procedure magnetic resonance imaging(MRI) study.Lesions were categorized as limited venous malformations and infiltrating venous malformations on the basis of MRI feature.Percutaneous endovascular therapy by direct injection was performed.After embolization of drainage vein with absolute ethanol,the following Bleomycine was injected.Results All patients were followed up for 12 months to 69 months with an average of 43 months.According to major symptoms,the results were excellent in 60 cases,good in 42 cases,fair in 62 cases and poor in 1 case.The better response was among the patients with limited venous malformations.Among of them 116 cases(95%) showed at least marked improvement.There were 6 sessions of tissue necrosis,5 sessions peripheral nerve palsy,10 sessions pigmentation,5 sessions blistering,and 89 sessions transient side effects related to Bleomycine such as fever and gastrointestinal irritation.No major complications such as cardio-pulmonary collapse and pulmonary fibrosis were reported.Conclusion Endovascular therapy for venous malformations was found to be safe and effective,which may be one of the techniques in the treatment of venous malformations.

Key words: GetLinkList(KeywordFilter(''Absolute ethanol, Bleomycine, Endovascular therapy, Venous malformations.''),''kw'',''CJFQ'')