Abstract: Platelet-rich fibrin (PRF) is a new generation of platelet concentrates. It is obtained by centrifuging whole blood without any additives. So the production procedure is very simple. It is rich in various growth factors and cytokines, which can accelerate tissue repair and regeneration. PRF has attracted more and more attention. But reported studies are mostly in dentistry and orthopedics. Reports in the plastic and reconstructive field are rare. In order to provide fully understanding for plastic surgeons regarding to PRF, the preparation techniques, derivatives and clinical applications in plastic surgery were reviewed in this paper.

Key words: Platelet-rich fibrin, 　Leukocyte- and platelet-rich fibrin, 　Advanced platelet-rich fibrin, 　Injectable platelet-rich fibrin