Objective　To evaluate and analyze the time window and influencing factors of various complications in breast

cancer (BC) patients undergoing implant-based breast reconstruction (IBBR). Methods　The retrospective study method was

used in this study. Extract the data to be analyzed from the inpatient medical records. The onset time of complications after breast

reconstruction in BC patients was described and summarized, and the related factors influencing the onset of complications were

analyzed by COX. Results　There were 129 cases of acute and long-term complications in 395 cases of breast reconstruction

surgery, and the incidence rate of complications was 32.66%. Among them, 73 patients (104 breasts) had at least one complication. Chemotherapy was the protective factor of postoperative hematoma (P<0.05). The indications of therapeutic mastectomy,

tissue expander implantation, prosthesis implantation in the anterior plane of pectoral muscle, preoperative radiotherapy for

IBBR, obesity and smoking were the risk factors for postoperative seroma (P<0.05). Preoperative radiation therapy was a risk

factor for postoperative necrosis of nipple areola/skin flap in patients with IBBR (P<0.05). The indication of therapeutic mastectomy and axillary lymph node dissection were the risk factors for postoperative infection in the surgical area (P<0.05). Preoperative radiotherapy, obesity, axillary lymph node dissection, and reconstruction support material Vicryl mesh were the risk factors

for prosthetic loss in patients with IBBR (P<0.05). Prosthesis implantation in the anterior plane of pectoral muscle, preoperative

radiotherapy for IBBR, chemotherapy and obesity were the risk factors for postoperative ripple/wrinkle (P<0.05). Radiotherapy

before IBBR and axillary lymph node dissection were the risk factors of capsular contracture (P<0.05). Conclusion　Postop

Breast reconstruction, 　Prosthesis implantation, 　Complication