Research progress of three-dimensional functional skin model construction in vitro

Abstract

Abstract:

Tissue engineering technology has been widely used in tissue and organ repair and has become an important

method of regenerative medicine technique. The appearance of tissue engineering skin provides a new method for the

treatment of large-area cutaneous defect in clinic. Because of the complicated skin-structure， it is an enormous challenge to

building a functional three-dimensional skin tissue engineering model to simulate or replace the original skin. Based on this，

from the aspects of cell types and sources， techniques， types， applications and prospects of skin tissue engineering models，

the latest progress of in vitro 3D functional skin tissue model construction was reviewed in order to provide a theoretical basis

for the construction of ideal skin tissue model.

Key words:

Three-dimensional, Tissue engineering, Skin model, Regenerative medicine

LI Yang, XI Taotao, ZHANG Bo, et al. Research progress of three-dimensional functional skin model construction in vitro[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2024, 20(2): 240-.

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Research progress of three-dimensional functional skin model construction in vitro

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