Journal of Tissue Engineering and Reconstructive Surgery ›› 2024, Vol. 20 ›› Issue (5): 542-.

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The clinical efficacy of blepharoplasty combined SVF-gel grafting for upper eyelid rejuvenation in Asian mid-aged and elderly female

  

  • Online:2024-10-08 Published:2024-11-25

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Abstract:

Objective To explore the feasibility of SVF-gel fat grafting to sunken upper eyelid combined with
blepharoplasty to improve upper eyelid laxity and depression in middle-aged and elderly women. Methods In this study，
214 patients who underwent blepharoplasty and ROOF layer SVF-gel fat filling were retrospectively studied. All patients
underwent abdominal liposuction and blepharoplasty under local anesthesia， and the SVF-gel was injected into the layers
between orbicularis oris muscle and periosteum layer of designed grafting area in the form of micro-droplets in ROOF layers
by using 25g blunt needles， finished by overcorrection of sunken upper eyelid. The laxity of upper eyelid was then corrected
by blepharoplasty with bridge skill， fully released septum fat and removed the appropriate amount of skin as well as muscle.
Standard photos were taken before and on the day after surgery，6 months after surgery， and aesthetic evaluation of upper
eyelid depression， satisfaction score and postoperative effect evaluation were also performed. Postoperative effect evaluation
included improvement of depression， double eyelid symmetry and complications. Results The 214 patients were all female，
with an average age of （38.61±10.22） years. The overall follow-up period was 6 to 23 months， and the average follow-up
period was （12.36±3.132） months. All the patients underwent bilateral blepharoplasty with SVF-gel fat grafting to ROOF 
layer， the amount of fat grafting ranged from 1.2-2 mL on one side， mean （1.535±0.282） mL on one side. The final overall
ratio of upper eyelid depression scored 3.569±1.517， while the preoperative ratio scored 1.115±0.502（n=428，P<0.000 1），
indicating a significant improvement in upper eyelid depression. The GAIS score was 2.384±0.193 （n=214）. Only 14
（6.54%） patients presented with hematomas within 7 days of surgery which resolved completely within two weeks. Eventually
at six months after surgery，47（21.96%） patients still had insufficient improvement of the upper eyelid depression and
required secondary fat grafting to achieve a better result， with a reoperation rate of 21.96%. Majority of patients were satisfied
with the results of the procedure， with an average satisfaction score of （3.974±0.473） out of 5（full mark）. Conclusion
SVF-gel fat grafting to ROOF layer combined with blepharoplasty is safe and effective in improving upper eyelid laxity and
depression in middle-aged and elderly women. SVF-gel has a good effect in the fine filling of the upper eyelid， and it can be
further developed with other surgical methods in the future.

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