Abstract: Aseptic loosening caused by wear and wear particles is the main cause for the failure of artificial ankle joints. The in vitro tests and computational simulation are important methods for pre-clinical evaluation of prosthetic wear performance. In this paper， the kinematic and dynamic curves used in wear studies of ankle prosthesis were compared. Afterwards， the results of the wear studies were summarized and analyzed. The results showed that： ① Due to the lack of ISO testing standard in the early stage， there are differences in the loading conditions of various studies， mainly reflected in axial load and anteroposterior displacement. Therefore， it is difficult to obtain the wear mechanism of ankle prostheses through the horizontal comparison. ② Foreign researchers have studied the effects of factors such as the implant design， materials， testing conditions， and lubricating media of artificial ankle joint prostheses on wear test results， but relevant literature has not been published in China. ③ The numerical simulation wear results of artificial ankle joint are similar to its in vitro test results， indicating that the validated simulation model can be used to predict the wear performance of ankle joint prostheses.

Key words: 　Ankle prosthesis, 　Wear, 　Loading conditions of wear, 　In-vitro wear test, 　Computational wear simulation