Objective To explore the surgical correction strategy and outcome of blepharoptosis in oculopharyngeal muscular dystrophy. Methods It was a retrospective case series study. The clinical records of 8 OPMD patients treated by

the same oculoplastic surgeon between January 2015 and December 2023 were analyzed. In the 8 patients，5 were male and 3 were female. The range of age was 55-64 years. All of the participants received massive levator resection for the correction of blepharoptosis. The preoperative and postoperative degree of change in upper eyelid height was measured. Paired sample t test was used to compare the preoperative and postoperative data. Results Postoperative follow up for patient was conducted for 6-73 months. All patients achieved satisfactory eyelid height within 6 months postoperatively. Mild blepharoptosis recurred in2 patient three and five years after surgery. The rest cases showed no recurrence. At 6 months postoperatively， the palpebral fissure height increased by （3.25±1.00） mm， and the MRD1 increased by （3.13±1.03） mm. The differences between the preoperative and postoperative data were significant （t=13.000，P=0.000；t=12.199，P=0.000）. Transient mild corneal epithelial defects occurred in 6 patients due to incomplete closure， which resolved by intensified ocular surface management. Conclusion Massive levator resection is an effective method for the correction of blepharoptosis in oculopharyngeal muscular dystrophy， with good aesthetic outcome， low recurrence rate and few complications

Oculopharyngeal muscular dystrophy, Blepharoptosis, Levator resection, Ocular plastic surgery