Journal of Tissue Engineering and Reconstructive Surgery ›› 2017, Vol. 13 ›› Issue (1): 51-53.doi: 10.3969/j.issn.1673-0364.2017.01.015

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The Etiology Research Progress of Hemifacial Microsomia

ZHANG Zhuo,WANG Chuan,CHEN Junbao   

  • Published:2020-07-23
  • Contact: 公益性行业科研专项基金

Abstract: Hemifacial microsomia (HFM) is the most common congenital facial anomaly except cleft lip and palate, which involves maldevelopment of craniofacial bones, muscles, soft tissues, facial nerves, auricles and extracranial organs. The disease affects unilaterally more frequently than bilaterally. The exact etiology and pathogenesis are still unclear. The reported pathogenesis includes genetics, environment and the mutual reaction. In this paper, the etiological investigations of HFM were classified and reviewed.

Key words: Hemifacial microsomia, Etiology, Vascular injury, Neural crest

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