Abstract: Objective To investigate the clinical efficacy and safety of locking plate internal fixation for the treatment of complex tibial plateau fractures. Methods From April 2010 to December 2012, 110 patients with complex tibial plateau fracture were divided into observation group (n=55) and control group (n=55). Patients in observation group were treated with locking plate internal fixation and patients in control group were treated with anatomic plate internal fixation. The general information, complications and clinical outcome of two groups were observed and compared. Results There were no significant differences in operation time and anatomical restoration rate between two groups (P>0.05). However, the peri-operative bleeding, time of hospitalization, loading time after operation, fracture healing time, range of knee motion 6 months after operation, HSS score of knee joint function 6 months after operation, complication rate and efficacy in observation group were significantly better than those in control group (P<0.05). Conclusion Locking plate internal fixation is effective and reliable for the treatment of complex tibial plateau fractures and is worthy of popularization.

Key words: Locking plate, Tibial plateau fracture, Efficacy, Safety