Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (1): 35-37.doi: 10.3969/j.issn.1673-0364.2009.01.010

• Original article • Previous Articles     Next Articles

Histological Observation on the Healing of Osteochondral Fracture in Rats after Ovariectomy

WANG Lei,LI Xiaoling   

  1. Department of Orthopaedic Surgery;Shanghai Sixth People′s Hospital;Shanghai Jiaotong University School of Medicine;Shanghai 200233;China.;
  • Published:2020-07-23

Abstract: Objective To explore the healing process of osteochondral fracture in rats after ovariectomy. Methods Sixteen female SD rats with a mean age of 4.5 months were involved in the study, eight of which underwent bilateral ovariectomy (OVX), while the others underwent sham operation (SHAM). Ten weeks later when the osteoporosis was confirmed, all the rats were suffered tibial plateau fracture (Schatzker Ⅳ) in right hind limb and fixed with two Kirschner wires in the same time. The rats were sacrificed on 6 weeks...

Key words: Osteoporosis, Osteochondral fracture, Ovariectomy

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