The research showed that the dendritic epidermal γδ T cells (DETCs) found in murine skin expressed aγδTCR composed of Vγ3Jγ1-Cγ1and Vδ1Dδ2Jδ2-Cδ chains which specifically expressed in murine skin. Activated DETCs produce several cytokines, growth factors and chemokines. All these factors were related to tissue repair, cell survival, proliferation, migration, recruitment, and play a key role in maintaining the epithelium integrity and repairing the epithelial tissue. In this paper, the functions of DETCs in maintaining the epithelium integrity and would repair were reviewed.