Journal of Tissue Engineering and Reconstructive Surgery >

2014 , Vol. 10 >Issue 6: 355 - 362

DOI: https://doi.org/10.3969/j.issn.1673-0364.2014.06.015

Review

Research Progress of Bone Morphogenetic Protein 2/7 Heterodimer

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  • Plastic Surgery Hospital, Weifang Medical University;

Online published: 2020-07-23

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Abstract

BMP2/7 heterodimer, a bone structure formation protein, has stronger osteogenesis inductive potential than its homodimer. So the study of BMP2/7 heterodimer has been one of the most important research directions in tissue engineering osteogenesis now. In this article, the osteo-inductive related experiments of BMP2/7 heterodimer were described, the differences of biological activity between heterodimer and homodimer were compared, and the mechanisms were overviewed.

Key words： Bone morphogenetic protein; Heterodimer; Bone tissue engineering; Osteogenic differentiation

Cite this article

GAO Tao,ZHOU Lulu,MIAO Chunlei,TANG Shengjian,LIU Fangjun . Research Progress of Bone Morphogenetic Protein 2/7 Heterodimer[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2014 , 10(6) : 355 -362 . DOI: 10.3969/j.issn.1673-0364.2014.06.015

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