Original article

Advancement of Drug-Delivery System in the Treatment of Osteomyelitis with Bone Defects

Expand
  • 1 The Second Military Medical University,Shanghai 200433,China;2 Changhai Hospital,The Second Military Medical University,Shanghai 200433,China.

Online published: 2020-07-23

Abstract

In 1970,the first bone substitute-PMMA was created and a lot of clinical studies were conducted.Clinical applications demonstrate good results and the mortality rate of osteomyelitis is significantly reduced.According to the degradation of materials,the drug-delivery system can be divided into biodegradable materials and non-degradable materials.As the bone substitute,the two types of materials were required to achieve the minimum inhibitory concentration in nature.The system types,preparation methods,the nature of the drug,and the drug release kinetics were reviewed.

Cite this article

LIU Chen,Yang Qingsong,SU Jiacan . Advancement of Drug-Delivery System in the Treatment of Osteomyelitis with Bone Defects[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2012 , 8(2) : 117 -120 . DOI: 10.3969/j.issn.1673-0364.2012.02.016

Options
Outlines

/