Original article

Influence Factors on Osteogenic Potential of Mesenchymal Stem Cells

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  • Research Center of Plastic Surgery Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100144,China.

Online published: 2020-07-23

Abstract

Mesenchymal stem cell(MSC) has broad prospects in the field of regenerative medicine and tissue engineering due to its highly self-renewal and multi-lineage differentiation ability.Although there are many researches about MSC osteogenic differentiation,its osteogenic efficiency is still very low both in vitro and in vivo.Therefore,how to improve the MSC osteogenic performance has become the focus of researchers.MSC osteogenic performance is influenced by many factors.In this review,the influence factors are discussed from four aspects: cell sources,approaches of isolation and purification,induction strategies and vascularization.

Cite this article

XIE Fangnan,KANG Ning,XIAO Ran . Influence Factors on Osteogenic Potential of Mesenchymal Stem Cells[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2012 , 8(4) : 225 -228 . DOI: 10.3969/j.issn.1673-0364.2012.04.013

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