Journal of Tissue Engineering and Reconstructive Surgery >

2009 , Vol. 5 >Issue 1: 12 - 55

DOI: https://doi.org/10.3969/j.issn.1673-0364.2009.01.004

Original article

Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering

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  • 1 Department of Dermatology;Tangdu Hospital;Fourth Military Medical University;Xi’an 710032;China;2 Research and Development Center for Tissue Engineering;School of Stomatology;Xi′an 710032;China.;

Online published: 2020-07-23

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Abstract

Objective To develop a scaffold material containing collagen-chondroitin sulfate-hyaluronic acid (Co-CS-HA) and corneal stromal cells corneal stroma tissue engineering. Methods Fabricated scaffold of Co-CS-HA for dermal tissue engineering and to evaluated its characteristics in vitro. The tissue-engineered corneal stroma was constructed by co-culturing rabbit keratocytes on Co-CS-HA scaffold. It was then transplanted into corneal stroma of rabbit. This tissue-engineered corneal stroma was observed and harve...

Key words： Collagen; Chondroitin sulfate; Hyaluronic acid; Scaffold; Corneal stroma

Cite this article

WANG Weihong,ZHANG Mi,XU Xiaolin,YU Chunyan,JIN Yan . Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009 , 5(1) : 12 -55 . DOI: 10.3969/j.issn.1673-0364.2009.01.004

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