Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering

doi:10.3969/j.issn.1673-0364.2009.01.004

Journal of Tissue Engineering and Reconstructive Surgery ›› 2009, Vol. 5 ›› Issue (1): 12-55.doi: 10.3969/j.issn.1673-0364.2009.01.004

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Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering

WANG Weihong¹,ZHANG Mi²,XU Xiaolin²,YU Chunyan¹,JIN Yan²

1 Department of Dermatology;Tangdu Hospital;Fourth Military Medical University;Xi’an 710032;China;2 Research and Development Center for Tissue Engineering;School of Stomatology;Xi′an 710032;China.;

Published:2020-07-23
Contact: 国家高技术发展计划项目(2006AA02A119)

Abstract

Abstract: Objective To develop a scaffold material containing collagen-chondroitin sulfate-hyaluronic acid (Co-CS-HA) and corneal stromal cells corneal stroma tissue engineering. Methods Fabricated scaffold of Co-CS-HA for dermal tissue engineering and to evaluated its characteristics in vitro. The tissue-engineered corneal stroma was constructed by co-culturing rabbit keratocytes on Co-CS-HA scaffold. It was then transplanted into corneal stroma of rabbit. This tissue-engineered corneal stroma was observed and harve...

Key words: Collagen, Chondroitin sulfate, Hyaluronic acid, Scaffold, Corneal stroma

CLC Number:

WANG Weihong,ZHANG Mi,XU Xiaolin,YU Chunyan,JIN Yan. Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009, 5(1): 12-55.

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Fabrication of Collagen-Chondroitin Sulfate-Hyaluronic Acid Scaffold and Its Biological Characteristics for Cornea Stroma Tissue Engineering

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