Journal of Tissue Engineering and Reconstructive Surgery >

2009 , Vol. 5 >Issue 4: 202 - 228

DOI: https://doi.org/10.3969/j.issn.1673-0364.2009.08.006

Original article

Effect of Botulinum Toxin Type A on the Expression of Substance P, Calcitionin Gene-Related Peptide, TGF-β1 and α-Smooth Muscle Actin a in Wound Healing in Rats

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  • Plastic and Cosmetic Department;Renji Hospital;Shanghai Jiaotong University School of Medicine;Shanghai 20001;China.;

Online published: 2020-07-23

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Abstract

Objective To investigate the effect of botulinum toxin type A on the expression of substance P and calcitionin gene-related peptide in wound healing. Methods Forty rats were randomly divided into Group C (Control) and Group E (Experimental), 20 rats in each group. The wound-healing model was established by excised four full-thickness skin (1 cm × 1 cm, circled the injection site) in the back of all SD rats 7 days after BTA injection. The area of wound was measured and calculated at the 3rd d and 7th day aft...

Key words： Botulinum toxin type A; Substance P; Calcitionin gene-related peptide; Wound healing; Scar

Cite this article

WANG Lin,TAI Ningzheng,CHEN Rui,FAN Zhihong . Effect of Botulinum Toxin Type A on the Expression of Substance P, Calcitionin Gene-Related Peptide, TGF-β1 and α-Smooth Muscle Actin a in Wound Healing in Rats[J]. Journal of Tissue Engineering and Reconstructive Surgery, 2009 , 5(4) : 202 -228 . DOI: 10.3969/j.issn.1673-0364.2009.08.006

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