Based on an oil development project in the South China Sea, the considerations of general layout for subsea production system (SPS) tied back to a cylinder shaped floating production, storage and offloading unit (FPSO) are summarized. Focus is put on the wellhead layout for the subsea production system which is just below the cylinder shaped FPSO, the hang mode of the production riser, umbilical and subsea power cable connected to the cylinder shaped FPSO, as well as the corresponding position arrangement. This research can provide reference for the general layout of similar subsea production systems in the future.