Digital electronic technology experiment is one of the specialized courses for the student majoring in electronics or related. The arbitrary waveform generator based on DDS is used to the digital electronic technology comprehensive virtual simulation experiment. This teaching case covers almost all core knowledge in the theory of digital electronic technology course, and has characteristic of strong comprehensive. It is convenient for students to master theoretical knowledge fragmentation in the course to build into a relatively complete knowledge system. Experiment results such as sine wave, rectangular wave, triangle wave, arbitrary wave and Lissajous figures can be observed through the oscilloscope. The students’ interests in learning are stimulated due to high presentation of experiment results. Practice shows that, comprehensive virtual simulation case can improve the students’ ability to design complex digital circuit system. It can also cultivate the students’ ability of practical innovation and engineering application. It achieved good teaching effect, and was beneficial to the improvement of teaching level.