诊断学理论与实践

诊断学理论与实践 ›› 2017, Vol. 16 ›› Issue (04): 425-429.doi: 10.16150/j.1671-2870.2017.04.016

• 论著 • 上一篇    下一篇

老年恶性肿瘤患者营养状况与一年内病死率的相关性分析

盛虹a, 曹伟新b   

  1. 上海交通大学医学院附属瑞金医院 a. 老年病科,b. 临床营养科,上海 200025
  • 收稿日期:2017-06-15 出版日期:2017-08-25 发布日期:2017-08-25
  • 通讯作者: 曹伟新 E-mail: cwx103@163.com
  • 基金资助:
    国家自然科学青年科学基金项目（81502693）

Correlation analysis on nutritional status of elderly malignant tumor patients and one-year mortality

SHENG Honga, CAO Weixinb   

  1. a. Department of Gerontology; b. Department of Clinical Nutrition, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Received:2017-06-15 Online:2017-08-25 Published:2017-08-25

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摘要： 目的: 探讨老年恶性肿瘤患者住院时的营养状况,分析营养不良与1年内病死率之间的关系。方法: 采用微型营养评定简表(mininutritional assessment-short form,MNA-SF)评估因确诊恶性肿瘤入住瑞金医院老年病科的老年患者的营养状况,同时测定患者体质量指数（body mass index,BMI）、血红蛋白、前白蛋白、白蛋白、三酰甘油、总胆固醇,跟踪随访其1年生存期。结果: 124例患者纳入研究,根据MNA-SF评分,营养正常（86例）、营养不良风险（33例）和营养不良（5例）的检出率分别为69.4%、26.6%和4.0%。所有患者中,总的1年内病死率为17.7%;3组患者中,以营养不良组为最高（3/5）。校正混淆变量后,COX回归模型提示营养不良将增加老年恶性肿瘤患者1年内死亡的风险。结论: 营养不良在一定程度上能够独立预测老年恶性肿瘤患者1年内的死亡风险。

关键词: 老年恶性肿瘤, 营养状况, 微型营养评定简表, 病死率

Abstract: Objectives: To investigate the nutritional status of elderly malignant tumor patients and to analyze the relation between malnutrition and one-year mortality. Methods: The nutritional status of elderly patients diagnosed as malignant tumor admitted in the department of gerontology, Ruijin Hospital were assessed by mininutritional assessment-short form (MNA-SF), and body mass index (BMI), hemoglobin, prealbumin, albumin, triglyceride and total cholesterol were measured and the patients were followed up for calculating the one-year survival. Results: One hundred and twenty four patients were included in the study. The incidence of nutrition, risky malnutrition and malnutrition was 69.4%, 26.6% and 4.0%, respectively, according to the MNA-SF. The one-year mortality was 17.7% in overall patients; and among the three groups, the one-year mortality was the highest(60%) in malnutrition group. After adjustment for confounding variables, COX regression model suggested that malnutrition can increase the risk of one-year mortality. Conclusions: Malnutrition can predict independently the risk of death of the elderly malignant tumor patients within one year.

Key words: Elderly malignant tumor, Nutritional status, Risky nutritional status, MNA-SF, Mortality

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