呼吸道及肠道微生物菌群与支气管哮喘的发病及治疗

doi:10.16150/j.1671-2870.2019.03.001

摘要/Abstract

关键词: 呼吸道, 肠道, 支气管哮喘, 机制

中图分类号:

R562.25

时国朝, 黄春容. 呼吸道及肠道微生物菌群与支气管哮喘的发病及治疗[J]. 诊断学理论与实践, 2019, 18(03): 241-245.

参考文献 33

[1]	Croisant S. Epidemiology of asthma: prevalence and burden of disease[J]. Adv Exp Med Biol, 2014, 795:17-29. doi: 10.1007/978-1-4614-8603-9_2 pmid: 24162900
[2]	Loftus PA, Wise SK. Epidemiology of asthma[J]. Curr Opin Otolaryngol Head Neck Surg, 2016, 24(3):245-249. doi: 10.1097/MOO.0000000000000262 URL
[3]	van Tilburg Bernardes E, Arrieta MC. Hygiene Hypothesis in Asthma Development: Is Hygiene to Blame?[J]. Arch Med Res, 2017, 48(8):717-726. doi: S0188-4409(17)30238-2 pmid: 29224909
[4]	McAleer JP, Kolls JK. Contributions of the intestinal microbiome in lung immunity[J]. Eur J Immunol, 2018, 48(1):39-49. doi: 10.1002/eji.201646721 pmid: 28776643
[5]	Alnahas S, Hagner S, Raifer H, et al. IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation[J]. Front Immunol, 2017, 8:1562. doi: 10.3389/fimmu.2017.01562 pmid: 29184554
[6]	Nguyen LD, Viscogliosi E, Delhaes L. The lung mycobiome: an emerging field of the human respiratory microbiome[J]. Front Microbiol, 2015, 6:89. doi: 10.3389/fmicb.2015.00089 pmid: 25762987
[7]	Simpson JL, Daly J, Baines KJ, et al. Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma[J]. Eur Respir J, 2016, 47(3):792-800. doi: 10.1183/13993003.00405-2015 pmid: 26647445
[8]	Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low gut microbiota diversity in early infancy precedes asthma at school age[J]. Clin Exp Allergy, 2014, 44(6):842-850. doi: 10.1111/cea.12253 pmid: 24330256
[9]	Arrieta MC, Stiemsma LT, Dimitriu PA, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma[J]. Sci Transl Med, 2015, 7(307):307ra152.
[10]	Thorburn AN, McKenzie CI, Shen S, et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites[J]. Nat Commun, 2015, 6:7320. doi: 10.1038/ncomms8320 pmid: 26102221
[11]	Furusawa Y, Obata Y, Fukuda S, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells[J]. Nature, 2013, 504(7480):446-450. doi: 10.1038/nature12721 URL
[12]	Noverr MC, Noggle RM, Toews GB, et al. Role of antibiotics and fungal microbiota in driving pulmonary allergic responses[J]. Infect Immun, 2004, 72(9):4996-5003. pmid: 15321991
[13]	Kim YG, Udayanga KG, Totsuka N, et al. Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE?[J]. Cell Host Microbe, 2014, 15(1):95-102. doi: 10.1016/j.chom.2013.12.010 URL
[14]	Li X, Leonardi I, Semon A, et al. Response to Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease[J]. Cell Host Microbe, 2018, 24(6):847-856. doi: 10.1016/j.chom.2018.11.003 URL
[15]	Erb-Downward JR, Thompson DL, Han MK, et al. Analysis of the lung microbiome in the "healthy" smoker and in COPD[J]. PLoS One, 2011, 6(2):e16384. doi: 10.1371/journal.pone.0016384 URL
[16]	Huang YJ, Nelson CE, Brodie EL, et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma[J]. J Allergy Clin Immunol, 2011, 127(2):372-381,e1-e3. doi: 10.1016/j.jaci.2010.10.048 URL
[17]	Li N, Qiu R, Yang Z, et al. Sputum microbiota in severe asthma patients: Relationship to eosinophilic inflammation[J]. Respir Med, 2017, 131:192-198. doi: 10.1016/j.rmed.2017.08.016 URL
[18]	Goldman DL, Chen Z, Shankar V, et al. Lower airway microbiota and mycobiota in children with severe asthma[J]. J Allergy Clin Immunol, 2018, 141(2):808-811,e7. doi: S0091-6749(17)31581-6 pmid: 29031597
[19]	Zhang Q, Cox M, Liang Z, et al. Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes[J]. PLoS One, 2016, 11(4):e0152724. doi: 10.1371/journal.pone.0152724 URL
[20]	Huang YJ, Nariya S, Harris JM, et al. The airway microbiome in patients with severe asthma: Associations with disease features and severity[J]. J Allergy Clin Immunol, 2015, 136(4):874-884. doi: 10.1016/j.jaci.2015.05.044 URL
[21]	Sverrild A, Kiilerich P, Brejnrod A, et al. Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome[J]. J Allergy Clin Immunol, 2017, 140(2):407-417,e11. doi: S0091-6749(16)32475-7 pmid: 28042058
[22]	Green BJ, Wiriyachaiporn S, Grainge C, et al. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma[J]. PLoS One, 2014, 9(6):e100645. doi: 10.1371/journal.pone.0100645 URL
[23]	Denner DR, Sangwan N, Becker JB, et al. Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways[J]. J Allergy Clin Immunol, 2016, 137(5):1398-1405,e3. doi: 10.1016/j.jaci.2015.10.017 pmid: 26627545
[24]	Durack J, Lynch SV, Nariya S, et al. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment[J]. J Allergy Clin Immunol, 2017, 140(1):63-75. doi: 10.1016/j.jaci.2016.08.055 URL
[25]	Goleva E, Jackson LP, Harris JK, et al. The effects of airway microbiome on corticosteroid responsiveness in asthma[J]. Am J Respir Crit Care Med, 2013, 188(10):1193-1201. doi: 10.1164/rccm.201304-0775OC URL
[26]	Vientós-Plotts AI, Ericsson AC, Rindt H, et al. Oral Probiotics Alter Healthy Feline Respiratory Microbiota[J]. Front Microbiol, 2017, 8:1287. doi: 10.3389/fmicb.2017.01287 pmid: 28744273
[27]	Setia A, Bhandari SK, House JD, et al. Development and in vitro evaluation of an Escherichia coli probiotic able to inhibit the growth of pathogenic Escherichia coli K88[J]. J Anim Sci, 2009, 87(6):2005-2012. doi: 10.2527/jas.2008-1400 pmid: 19286822
[28]	Pochard P, Gosset P, Grangette C, et al. Lactic acid bacteria inhibit TH2 cytokine production by mononuclear cells from allergic patients[J]. J Allergy Clin Immunol, 2002, 110(4):617-623. doi: 10.1067/mai.2002.128528 URL
[29]	Hougee S, Vriesema AJ, Wijering SC, et al. Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: a bacterial strain comparative study[J]. Int Arch Allergy Immunol, 2010, 151(2):107-117. doi: 10.1159/000236000 URL
[30]	Pascal M, Perez-Gordo M, Caballero T, et al. Microbiome and Allergic Diseases[J]. Front Immunol, 2018, 9:1584. doi: 10.3389/fimmu.2018.01584 URL
[31]	Durack J, Kimes NE, Lin DL, et al. Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation[J]. Nat Commun, 2018, 9(1):707. doi: 10.1038/s41467-018-03157-4 URL
[32]	Chen YS, Jan RL, Lin YL, et al. Randomized placebo-controlled trial of lactobacillus on asthmatic children with allergic rhinitis[J]. Pediatr Pulmonol, 2010, 45(11):1111-1120. doi: 10.1002/ppul.21296 URL
[33]	van Nimwegen FA, Penders J, Stobberingh EE, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy[J]. J Allergy Clin Immunol, 2011, 128(5):948-955,e1-e3. doi: 10.1016/j.jaci.2011.07.027 URL

呼吸道及肠道微生物菌群与支气管哮喘的发病及治疗

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 33

相关文章 15

编辑推荐

Metrics

本文评价

[1]	陈宏, 沈银忠. 人类免疫缺陷病毒感染/艾滋病合并结核病的诊治进展[J]. 诊断学理论与实践, 2022, 21(04): 530-534.
[2]	汤建平, 龚邦东. 干燥综合征的诊治现状、挑战和思考[J]. 诊断学理论与实践, 2022, 21(03): 291-298.
[3]	郭业兵, 郑金峰. 阴道壁胃肠道外间质瘤一例报道并文献复习[J]. 诊断学理论与实践, 2022, 21(03): 405-407.
[4]	许飞, 尹明月, 王伟, 董治亚, 陆文丽, 余熠, 王歆琼, 王俊祺, 肖园. 性早熟女童肠道菌群和抗生素耐药性的宏基因组分析[J]. 诊断学理论与实践, 2022, 21(01): 52-61.
[5]	罗雅方, 徐倩玥, 余红. 尘螨在特应性皮炎中的致病机制及相关免疫治疗应用研究进展[J]. 诊断学理论与实践, 2021, 20(06): 592-595.
[6]	苏长青. 从基础研究到临床转化应用谈肝癌的诊治进展[J]. 诊断学理论与实践, 2021, 20(05): 427-433.
[7]	章淼滢, 罗飞宏. 儿童单基因糖尿病诊治进展及诊断策略[J]. 诊断学理论与实践, 2021, 20(03): 229-232.
[8]	董治亚, 戴彤彤. 肠道微生物群与儿童生长间相关性的研究进展及临床意义[J]. 诊断学理论与实践, 2021, 20(03): 234-238.
[9]	顾怡瑾, 李安琪, 董磊, 许海敏, 申霞, 谢嘉玲, 袁菲, 王朝夫. 原发、复发及转移胃肠道间质瘤KIT及PDGFRA突变与临床病理特征间的关系[J]. 诊断学理论与实践, 2021, 20(03): 257-264.
[10]	周新, 张旻. 中国支气管哮喘防治指南（2020年版）解读[J]. 诊断学理论与实践, 2021, 20(02): 138-143.
[11]	李林, 安静静, 王俊祺, 王歆琼, 董治亚. 16S rRNA第二代测序技术分析特发性身材矮小儿童肠道菌群构成的特征及相关发病机制研究[J]. 诊断学理论与实践, 2021, 20(02): 149-154.
[12]	李惠, 冯洁, 韩立中. 高通量测序技术分析无特定病原体级实验小鼠肠道的菌群组成[J]. 诊断学理论与实践, 2020, 19(1): 55-62.
[13]	安静静, 王俊祺, 肖园, 陆文丽, 李林, 王伟, 董治亚. 16S rRNA高通量测序分析肠道菌群对小于胎龄大鼠生长追赶的影响及其可能的机制[J]. 诊断学理论与实践, 2020, 19(04): 375-380.
[14]	徐兆平, 王浩飞. ZNF692基因在肾透明细胞癌中的表达及其与患者预后间关系的研究[J]. 诊断学理论与实践, 2020, 19(03): 292-296.
[15]	陈瑶瑶, 顾爱华. 氧化三甲胺与心血管疾病关系的研究进展[J]. 诊断学理论与实践, 2019, 18(2): 237-240.