Objective: To investigate whether the existed local inflammation and general micro-inflammation during arteriovenous fistula operation would predict the stenosis of arteriovenous fistula(AVF) in site of cannulation with buttonhole technique thereafter. Methods: Twenty-three patients with chronic kidney disease(CKD) stage 5 were allocated into 2 groups according to the expression of MCP-1 on the wall of radial artery during the operation of constructing AVF: low MCP-1 expression group and high MCP-1 expression group. All of the AVF were cannulated with buttonhole technique and followed up for 48 months. Results: The stenosis rate of cannulation site was 5 per 560 patient-month in low MCP-1 expression group, 8 per 209 patient-month in high MCP-1 expression group (u=-2.080, P<0.05). Compared with low MCP-1 expression group, the Hazzar ratio for high MCP-1 expression group to develop cannulation site stenosis was 0.08 (95% CI: 0.02-0.32, P<0.01). COX analysis revealed that high MCP-1 expression on radial artery and high level of hsCRP were the risk factors for cannulation site stenosis and the HR were 1.008 and 17.84, respectively(P<0.05). Conclusions: The expression of MCP-1 on radial artery and the level of hsCRP could predict the stenosis of the cannulation site of AVF with buttonhole.
LIU Ling, ZHANG Chen, LI Mingxin, QIN Ximiao, HUANG Bihong, XUE Jun
. Correlation of expression of MCP-1 on wall of radial artery with stenosis of cannulation site in arteriovenous fistula with buttonhole in hemodialysis patients[J]. Journal of Diagnostics Concepts & Practice, 2017
, 16(04)
: 394
-398
.
DOI: 10.16150/j.1671-2870.2017.04.010
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