Objective: To investigate the current teaching situation of hematology, and to explore teaching methods for improving interest and satisfaction in inmedical students. Methods: A questionnaire of present teaching situation of hematology was designed, and 240 medical students who were receiving medical clinical practice teaching in Ruijin Hospital were recruited and surveyed. Master degrees in knowledge of hematology theory, teaching frequency and teaching methods were explored, as well as effect of clinical practice opportunities on learning satisfaction and interests in students. The software SPSS 23.0 was used to analyze statistics. Results: Overall 41.4% of students were interested in hematology after clinical practice, while 40.6% of students showed satisfaction in hematology. Compared with those who were taught less than twice a week, students who receive teather's guide at least twice a week were more interested in hematology. Conclusions: Since hematology is a subject quite difficult to understand, it is important to improve the way of teaching, and combine theories with clinical practice to achieve better teaching effectiveness, which may stimulate students' interest and promote independent learning in learning hematology.