WANG Xuefeng
Editor in-Chief of Journal of Diagnostics Concepts & Practice
Chief Physician, Professor, and PhD Advisor, Ruijin Hospital, Shanghai
Vice Dean, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine
Director, Department of Laboratory Medicine, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Director, Department of Clinical Transfusion, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Director, Center for Laboratory Diagnostics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai Leading Talent
Chairman, Shanghai Society of Laboratory Medicine
Vice Chairman, National Clinical Transfusion Committee
Vice Chairman, Hematology and Body Fluids Group, Chinese Society of Laboratory Medicine
Editor-in-Chief, Journal of Diagnostics Concepts & Practice
Executive Editor-in-Chief, LabMed Discovery
Associate Editor-in-Chief, Laboratory Medicine, Journal of Microcirculation, Journal of Thrombosis and Hemostasis
Long-term dedication to research on the diagnosis and treatment of bleeding and thrombotic disorders, with extensive experience in the diagnosis and management of various bleeding conditions, particularly severe hemorrhages.
Recent Representative Publications:
[1] Xuefei Ma, Weifen Sun, Yilu Li, Yun Tan, Xuefeng Wang, Kankan Wang.Super-Enhancer-Associated Long Noncoding RNA Lnc-SPI1U Participates in PU.1 Feedback Regulation By Interacting with HNRNPH1 and[J].Blood,2024,144:1356.https://doi.org/10.1182/blood-2024-194099.
[2]Wenman WU, Rui Wang, Qin Xu, Guanzheng Wang, Shifeng Jiang, Can Lou, Xi Wu, Yanyan Shao, Yeling Lu, Yu Liu, Guanquan Xu, Qiulan Ding, Xiaobo Hu, Xuefeng Wang, Jing Dai; Thrombosis Caused By a Novel Coagulation Factor IX Mutation (FIX Shanghai II)[J]. Blood,2023,142 (Supplement 1):1233. https://doi.org/10.1182/blood-2023-184596.
[3] Enhao Li, Zekun Li, Jing Dai, Guoqing Liu, Jie Sun, Zhenping Chen, Runhui Wu, Xuefeng Wang, Wenman WU; Single-Cell Sequencing of Immune Cells from Hemophilia a Patients with Inhibitors and Acquired Hemophilia a Patients[J]. Blood,2022,140 (Supplement 1):8428–8429. https://doi.org/10.1182/blood-2022-169345.
[4] Jianwei Zeng, Zimei Shu, Qian Liang, Jing Zhang, Wenman Wu, Xuefeng Wang, Aiwu Zhou; Structural basis of von Willebrand factor multimerization and tubular storage[J]. Blood,2022,139 (22):3314–3324. https://doi.org/10.1182/blood.2021014729.
[5]Chen W, Wang D, Deng X, Zhang H, Dong D, Su T, Lu Q, Jiang C, Ni Q, Cui Y, Zhao Q, Wang X, Xiao Y, Peng Y. Bile acid profiling as an effective biomarker for staging in pediatric inflammatory bowel disease[J]. Gut Microbes,2024,16(1):2323231. https://doi.org/10.1080/19490976.2024.2323231.
[6]Liang Q, Zhang Z, Ding B, Shao Y, Ding Q, Dai J, Hu X, Wu W, Wang X. A noncanonical splicing variant c.875-5 T > G in von Willebrand factor causes in-frame exon skipping and type 2A von Willebrand disease[J]. Thromb Res,2024,236:51-60.https://doi.org/10.1016/j.thromres.2024.02.002.
[7]Ding B, Mao Y, Li Y, Xin M, Jiang S, Hu X, Xu Q, Ding Q, Wang X. A novel GATA1 variant p.G229D causing the defect of procoagulant platelet formation[J]. Thromb Res,2024,234:39-50. https://doi.org/10.1016/j.thromres.2023.12.015.
[8] Zhou S, Wu X, Song Y, Li L, Shi C, Lai Z, Ding Q, Wu W, Dai J, Wang X, Lu Y. Ser252Asn Mutation Introduces a New N-Linked Glycosylation Site and Causes Type IIb Protein C Deficiency[J]. Thromb Haemost,2024,124(5):459-470. https://doi.org/10.1055/s-0043-1777133.
[9]Wu X, Li L, Lu Z, Hu X, Lu Y, Liu Y, Xu G, Ding Q, Wang X, Wu W, Jin P, Dai J. Heterozygous Prothrombin Mutation-Associated Thrombophilia[J]. Thromb Haemost,2025,125(1):69-81. https://doi.org/10.1055/a-2350-8338.
[10] Lou C, Jiang J, Chen W, Zhang Z, Xu G, Liu Y, Dai J, Ding Q, Wang X, Wei H, Wu Y, Xu Q, Wu W. Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients[J]. Br J Haematol,2023,202(3):623-635.https://doi.org/10.1111/bjh.18768.
[11]Liu G, Sun J, Li Z, Chen Z, Wu W, Wu R. F9 mutations causing deletions beyond the serine protease domain confer higher risk for inhibitor development in hemophilia B[J]. Blood,2023,141(6):677-680. https://doi.org/10.1182/blood.2022017871.
Sergio Bernardini (Italy)
Editorial Board Member of Journal of Diagnostics Concepts & Practice
Professor of Clinical Biochemistry and Clinical Molecular Biochemistry, Department of Experimental Medicine, University of Rome Tor Vergata
Director, Department of Integrated Diagnostics, Tor Vergata University Hospital
Associate Editor-in-Chief of LabMed Discovery
Editorial Board Member of Journal of Applied Laboratory Medicine
Recent Articles：
[1] Kumar M, Ali W, Yadav K, Kaumri S, Mishra S, Nardi P, Iellamo F, Bernardini S, Pradhan A, Perrone MA. High-Density Lipoprotein-Associated Paraoxonase-1 (PON-1) and Scavenger Receptor Class B Type 1 (SRB-1) in Coronary Artery Disease: Correlation with Disease Severity[J]. J Clin Med,2024,13(18):5480. doi: 10.3390/jcm13185480.
[2] Tomassetti F, Calabrese C, Bertani F, Cennamo M, Diamanti D, Giovannelli A, Guerranti R, Leoncini R, Lorubbio M, Ognibene A, Nicolai E, Pelagalli M, Pieroni C, Bernardini S, Pieri M. Performance Evaluation of Automated Erythrocyte Sedimentation Rate (ESR) Analyzers in a Multicentric Study[J]. Diagnostics (Basel),2024,14(18):2011. doi: 10.3390/diagnostics14182011.
[3] Rapanotti MC, Cenci T, Scioli MG, Cugini E, Anzillotti S, Savino L, Coletta D, Di Raimondo C, Campione E, Roselli M, Bernardini S, Bianchi L, De Luca A, Ferlosio A, Orlandi A. Circulating Tumor Cells: Origin, Role, Current Applications, and Future Perspectives for Personalized Medicine[J]. Biomedicines,2024,12(9):2137. doi: 10.3390/biomedicines12092137.
[4] Gruson D, Fux E, Kemalo?lu ?z T, Gouget B, Lee W, Shah S, Liu Y, Ebert S, Greaves R, Bernardini S, Yang HS, Figueroa Montes L. Contribution of laboratory medicine and emerging technologies to cardiovascular risk reduction via exposome analysis: an opinion of the IFCC Division on Emerging Technologies[J]. Clin Chem Lab Med,2024. doi: 10.1515/cclm-2024-0788.
[5] Prezioso C, Limongi D, Checconi P, Ciotti M, Legramante JM, Petrangeli CM, Leonardis F, Giovannelli A, Terrinoni A, Bernardini S, Minieri M, D'Agostini C. Role of miR-9 in Modulating NF-κB Signaling and Cytokine Expression in COVID-19 Patients[J]. Int J Mol Sci,2024,25(16):8930. doi: 10.3390/ijms25168930.
Dongchon Kang（Japan）
Editorial Board Member of Journal of Diagnostics Concepts & Practice
Professor, Department of Clinical Chemistry and Laboratory Medicine, Faculty of Medical Sciences, Kyushu University
Professor Kang's research is extensive, covering multiple fields such as mitochondria, mitochondrial DNA, molecular biology, cell biology, and internal medicine, with research in these areas being highly interdisciplinary and mutually integrated.
Recent articles：
[1] Miki K, Yagi M, Kang D, Kunisaki Y, Yoshimoto K, Uchiumi T. Glucose starvation causes ferroptosis-mediated lysosomal dysfunction[J]. iScience,2024,27(5):109735. doi: 10.1016/j.isci.2024.109735
[2] Fujinuma S, Nakatsumi H, Shimizu H, Sugiyama S, Harada A, Goya T, Tanaka M, Kohjima M, Takahashi M, Izumi Y, Yagi M, Kang D, Kaneko M, Shigeta M, Bamba T, Ohkawa Y, Nakayama KI. FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation[J]. Cell Rep,2023,42(5):112530. doi: 10.1016/j.celrep.2023.112530
[3] Ueda S, Yagi M, Tomoda E, Matsumoto S, Ueyanagi Y, Do Y, Setoyama D, Matsushima Y, Nagao A, Suzuki T, Ide T, Mori Y, Oyama N, Kang D, Uchiumi T. Mitochondrial haplotype mutation alleviates respiratory defect of MELAS by restoring taurine modification in tRNA with 3243A > G mutation[J]. Nucleic Acids Res,2023,51(14):7480-7495. doi: 10.1093/nar/gkad591.
[4] Nakashima K, Kunisaki Y, Hosokawa K, Gotoh K, Yao H, Yuta R, Semba Y, Nogami J, Kikushige Y, Stumpf PS, MacArthur BD, Kang D, Akashi K, Ohga S, Arai F. POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis[J]. Commun Biol,2023,6(1):996. doi: 10.1038/s42003-023-05374-0.
[5] Matsuda S, Nakayama M, Do Y, Ishiuchi T, Yagi M, Wanrooij S, Nakada K, Wei FY, Ichiyanagi K, Sasaki H, Kang D, Yasukawa T. TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA[J]. Commun Biol,2025,8(1):202. doi: 10.1038/s42003-025-07645-4.
Professor HUANG Hui
Editorial Board Member of Journal of Diagnostics Concepts & Practice
Chief Physician, Professor, and PhD Advisor, Peking Union Medical College Hospital
Deputy Director, Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital
Committee Member, Respiratory Society of Beijing Medical Association
Corresponding Editorial Board Member, Chinese Journal of Tuberculosis and Respiratory Diseases and National Medical Journal of China (Chinese Edition)
Extensive clinical experience and research focus in the diagnosis and treatment of interstitial lung diseases and rare/uncommon respiratory infectious diseases.
Recent Representative Publications (# Corresponding Author):
[1] Chen Qi, Shi Yujie, Chen Ruxuan, Xu Kai, Huang Cheng, Li Ji, Li Ziyi, Wang Mengqi, Shao Chi, Huang Hui#, Wang Mengzhao. Clinical analysis of patients with idiopathic pulmonary fibrosis concurrent with surgery resectable lung cancer: a retrospective cohort study from perspective of ILD physicians. BMC Pulm Med. 2025 Apr 29;25(1):205. doi: 10.1186/s12890-025-03680-3
[2] Yang Zhongyi, Li Zhiyi, Liu Zhigang, Li Wenqi, Jiao Ran, Liu Yuming, Chen Ruxuan, Shi Yujie, Zhang Tiantian, Liu Jing, Meng Lingxin, Chai Dan, Xu Zuojun, Li Xiaohe, Zhou Honggang, Huang Hui#. Ruxolitinib attenuates bleomycin-induced pulmonary fibrosis in mice by modulating macrophage polarization through the JAK/STAT signaling pathway. Int Immunopharmacol. 2025:161:114962. doi: 10.1016/j.intimp.2025.114962.
[3] Shi Yujie, Li Yanyan, Chen Ruxuan, Fang Nan, Wang Mengqi, Li Zhiyi, Chen Qi, Shao Chi, Lin Mingbao, Huang Hui#. Peripheral and pulmonary telomere lengths in patients with non-idiopathic pulmonary fibrosis interstitial lung diseases. BMC Pulm Med. 2025;25(1):368.
doi: 10.1186/s12890-025-03865-w.
[4] Shi Yujie, Chen Ruxuan, Sun Hongli, Xu Kai, Wang Mengqi, Li Zhiyi, Shao Chi, Huang Hui#. Characteristics and prognostic analysis of Pneumocystis jirovecii pneumonia in connective tissue diseases patients with interstitial lung disease: a retrospective study. Clin Rheumatol. 2025;44(4):1653-1663. doi: 10.1007/s10067-025-07392-1.
[5] Chi Shao, Yujie Shi, Ruxuan Chen, Xiangning Liu, Hui Huang#, Yang Zhao, Kai Xu, Keqi Chen, Mengzhao Wang, Zuojun Xu. Risk factors associated with COVID-19 pneumonia in Chinese patients with pre-existing interstitial lung disease during the SARS-CoV-2 pandemic. J Med Virol. 2023;95(9):e29098. Doi: 10.1002/jmv.29098.
[6] Chen R, Shi Y, Fang N, Shao C, Huang H#, Pan R, Xu Y, Wang M, Liu X, Xu K, Zhu R, Wang M. Bronchoalveolar lavage fluid analysis in patients with checkpoint inhibitor pneumonitis. Cancer Immunol Immunother. 2024;73(11):235. doi:10.1007/s00262-024-03834-y.
[7] Liu B, Jiang Q, Chen R, Zhang H, Xia Q, Shao C, Liu X, Wang M, Shi Y, Zhu J, Zhao R, Jiang H, Gao S, Li X, Zhou H, Yang C, Huang H#. Tacrolimus alleviates pulmonary fibrosis progression through inhibiting the activation and interaction of ILC2 and monocytes. Int Immunopharmacol. 2024;132:111999. doi:10.1016/j.intimp.2024.111999.
[8] Ruxuan Chen, Chi Shao, Xiangning Liu, Hui Huang#, Boju Pan, Kai Xu, Rui Zhu, Mei Li, Yang Zhao, Keqi Chen, Mengzhao Wang, Zuojun Xu. Clinical spectrum of Chinese hospitalized lung cancer patients with concomitant interstitial lung disease: before and after the new era of LC treatment. Clin Exp Med. 2023 Jan 30;1-10. doi: 10.1007/s10238-023-00999-1.
[9] Chi Shao, Yuxin Sun, Hui Huang#, Zeyu Zhang, Ruili Pan, Kai Xu, Xin Zhang, Ying Zhang, Zuojun Xu. Myositis specific antibodies are associated with isolated anti-Ro-52 associated interstitial lung disease. Rheumatology. 2022;61:1083-1091. doi: 10.1093/rheumatology/keab488
[10] Shan Li#, Yuxin Sun#, Chi Shao, Hui Huang#, Qian Wang, Kai Xu, Xin Zhang, Peng Liu, Xiaofeng Zeng, Zuojun Xu. Prognosis of adult idiopathic inflammatory myopathy-associated interstitial lung disease: a retrospective study of 679 adult cases. Rheumatology. 2021;60:1195-1204.
