Original articles

The predictive value of IgG anti-A/B titer score on severity of hemolytic disease of newborn

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  • 1. Shanghai First Maternity and Infant Hospital, Shanghai 200040, China;
    2 Shanghai Blood Center, Shanghai 200051, China

Received date: 2018-03-19

  Online published: 2018-08-25

Abstract

Objective: To study the correlation of IgG anti-A/B titer score and the severity of hemolytic disease of newborn. Methods: The red blood cell count, hemoglobin and hematocrit value of 27 newborn with hemolytic disease and the IgG anti-A/B titer and titer score of their mother were measured and their correlations were analyzed. Results: With the increase in IgG anti-A/B titer and titer score of mother, the red blood cell count, hemoglobin and hematocrit values of newborn with hemolytic disease decreased. At the same IgG anti-A/B titer, the higher the titer score, the lower the red blood count, hemoglobin and hematocrit value were. Conclusions: According to the correlation analysis, the titer score is more closely related to the severity of hemolytic disease of newborn. For hemoglobin, the correlation coefficient was -0.966. The IgG anti-A/B titer score was of more clinical significance in predicting the severity of hemolytic disease in newborn.

Cite this article

TANG Weixian, JIN Sha, ZHENG Jiewei, YE Zhen, LIU Xi, SHEN Wei . The predictive value of IgG anti-A/B titer score on severity of hemolytic disease of newborn[J]. Journal of Diagnostics Concepts & Practice, 2018 , 17(04) : 449 -452 . DOI: 10.16150/j.1671-2870.2018.04.018

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