内科理论与实践 ›› 2024, Vol. 19 ›› Issue (06): 417-421.doi: 10.16138/j.1673-6087.2024.06.12

• 讲座 • 上一篇    下一篇

重视干燥综合征的早期诊断

范凯健1,2, 刘金渝2, 赵福涛1()   

  1. 1.上海交通大学医学院附属第九人民医院风湿免疫科,上海 200011
    2.上海市崇明区精神卫生中心药剂科,上海 202150
  • 收稿日期:2024-10-15 出版日期:2024-12-26 发布日期:2025-03-11
  • 通讯作者: 赵福涛 E-mail: ftzhao@moisten.org
  • 基金资助:
    上海市卫生健康委员会科研项目(202140411)

Importance of early diagnosis of Sjögren syndrome

FAN Kaijian1,2, LIU Jinyu2, ZHAO Futao1()   

  1. 1. Department of Rheumatology and Immunology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
    2. Department of Pharmacy, Mental Health Center, Chongming District, Shanghai 202150, China
  • Received:2024-10-15 Online:2024-12-26 Published:2025-03-11

摘要:

干燥综合征(Sjögren syndrome,SS)的早期诊断存在一些挑战和未满足的需求,如诊断时腺体功能障碍突出和诊断延迟时间长。这些挑战源于对SS早期缺乏充分了解。临床和实验研究结果表明,SS的早期诊断和干预有助于延缓疾病进展,并减少并发症发生的风险。为实现SS的早期诊断和治疗,需识别更多SS早期阶段的有用生物标志物,并确定SS发病的高危人群。同时,应对这些高危人群进行适当的筛查,以促进SS的早期诊断。

关键词: 干燥综合征, 早期诊断, 流行病学

Abstract:

There are several challenges in the early diagnosis of Sjögren syndrome (SS), such as prominent glandular dysfunction in patients to make long diagnostic delays. These challenges are mainly attributed to the lack of adequate understanding of the early-stage characteristic of SS. Clinical and experimental studies have shown that early diagnosis and intervention in SS can help delay disease progression and reduce the risk of complications. To achieve early diagnosis and treatment of SS, it’s necessary to identify more useful biomarkers for the early stages of SS, and to identify high-risk people for SS through appropriate screening.

Key words: Sjögren syndrome, Early diagnosis, Epidemiology

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