Journal of Internal Medicine Concepts & Practice ›› 2024, Vol. 19 ›› Issue (04): 273-277.doi: 10.16138/j.1673-6087.2024.04.11

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Study on efficacy and safety of Dioscorea bublifera L. in treatment of Graves disease

CUI Yifan, ZHANG Ruixiang, WEI Xiao, LIU Chao   

  1. Endocrine and Diabetes Center, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing University of Traditional Chinese Medicine, Jiangsu Branch of China Academy of Chinese Medical Science,Nanjing 210028,China
  • Received:2023-12-18 Online:2024-08-28 Published:2024-11-11

Abstract:

Hyperthyroidism is most common in Graves disease (GD), and traditional antithyroid medicine are often difficult to achieve satisfactory efficacy, and high recurrence rate and long course of treatment are the most prominent problems. Huangyaozi(Dioscorea bublifera L.), a traditional Chinese medicine, has the effect of “Xiao Ying” and has been widely used in the treatment of GD in recent years, but long-term use may cause liver and kidney damage. Therefore, more research on the efficacy and safety of Huangyaozi need to be done in the treatment of GD.

Key words: Dioscorea bublifera L., Graves disease, Efficacy, Safety, Diosgenin, Hepatotoxicity

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