Journal of Internal Medicine Concepts & Practice >

2022 , Vol. 17 >Issue 06: 453 - 456

DOI: https://doi.org/10.16138/j.1673-6087.2022.06.006

Original article

Inverse correlation between asymptomatic erosive esophagitis and chronic active gastritis

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  • a. Department of General Practice, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    b. Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2022-05-17

  Online published: 2023-02-27

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Abstract

Objective To explore the correlation between asymptomatic erosive esophagitis (AEE) and chronic active gastritis. Methods In this case-control study, the individuals without gastroesophageal reflux symptoms underwent esophagogastroduodenoscopy for routine health checkup were included and divided into two groups. AEE group was consisted of subjects with erosive esophagitis but without gastroesophageal reflux symptoms. The control group was consisted of individuals with neither gastroesophageal reflux symptoms nor endoscopic erosive esophagitis. The demographics, gastroscopy and histopathologic results were collected. Results A total of 1 818 individuals were included in the study, including 209 subjects in AEE group and 1 609 subjects in the control group. In multivariate Logistic regression analysis, advanced age (P=0.008), higher body mass index (P<0.001) and hiatus hernia (P<0.001) were associated with an increased risk of AEE. Female(P<0.001), bile reflux (P=0.007) and chronic active gastritis (P=0.041) were associated with a decreased risk of AEE. Conclusions Chronic active gastritis exhibited inverse relationship with AEE.

Key words： Esophagitis; Chronic gastritis; Bile reflux

Cite this article

SUN Chao, YAO Weiyan, TANG Yuming, HUANG Jia, ZHU Ying . Inverse correlation between asymptomatic erosive esophagitis and chronic active gastritis[J]. Journal of Internal Medicine Concepts & Practice, 2022 , 17(06) : 453 -456 . DOI: 10.16138/j.1673-6087.2022.06.006

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