Journal of Internal Medicine Concepts & Practice >

2024 , Vol. 19 >Issue 04: 269 - 272

DOI: https://doi.org/10.16138/j.1673-6087.2024.04.10

Review

Impact of maternal hyperthyroidism during pregnancy on neurological and psychiatric development of offspring

  • YANG Ao ,
  • ZHANG Peiheng ,
  • ZHANG Yang ,
  • GAO Ying
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  • Department of Endocrinology, Peking University First Hospital, Beijing 100034, China

Received date: 2024-07-01

  Online published: 2024-11-11

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Abstract

Gestational hyperthyroidism can significantly increase health risks to both mother and fetal. However, there are few reports on its impact on the neuropsychological development of offspring. This article reviews the literature related to the effect of hyperthyroidism during pregnancy on brain structure, intelligence quotient (IQ) and neuropsychiatric disorders of offsprings. It was found that hyperthyroidism during pregnancy may be associated with reduced brain volume and cortical gray matter volume, lower IQ, and increase the risk of depression in offspring. However, its’ relationship with other mental and emotional well-being disorder of the offspring is unclear.

Key words： Pregnancy; Hyperthyroidism; Neurological development; Mental disorders; Offspring

Cite this article

YANG Ao , ZHANG Peiheng , ZHANG Yang , GAO Ying . Impact of maternal hyperthyroidism during pregnancy on neurological and psychiatric development of offspring[J]. Journal of Internal Medicine Concepts & Practice, 2024 , 19(04) : 269 -272 . DOI: 10.16138/j.1673-6087.2024.04.10

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