Journal of Internal Medicine Concepts & Practice >

2024 , Vol. 19 >Issue 06: 413 - 416

DOI: https://doi.org/10.16138/j.1673-6087.2024.06.11

Case report

A case of primary skeletal muscle peripheral T-cell lymphoma diagnosed by 18F-FDG-PET/CT

  • AI Xiangyan ,
  • LIU Yang ,
  • CHENG Fang ,
  • ZHAO Futao
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  • Department Rheumatology and Immunology, Shanghai Ninth People’s Hospital，Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Received date: 2024-11-05

  Online published: 2025-03-11

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Abstract

Primary skeletal muscle lymphoma is rare, and primary skeletal muscle non-specified peripheral T-cell lymphoma (PTCL-NOS) is even rarer. It is prone to be misdiagnosed and missed as its lack of specificity of clinical manifestations. At present, its diagnosis primarily relies on 18F-FDG-PET/CT to screen hypermetabolic lesions and tissue biopsy to confirm it. This article reports a case of oropharyngeal ulcers accompanied by fever as the main clinical manifestations, while there were no atypical cells found in multiple biopsies of the ulcer sites. PET/CT showed heterogeneous hypermetabolism in the calf muscles of two legs and the pharynx. Finally, the patient diagnosis was confirmed as primary skeletal muscle PTCL-NOS through calf muscle biopsy, hematoxylin and eosin staining (HE) staining and immunohistochemistry. The diagnostic process of the case was challenging. It suggests that recognition of primary skeletal muscle PTCL-NOS needs to be improved to achieve early diagnosis and better prognosis.

Key words： Oropharyngeal ulcers; Primary peripheral T-cell lymphoma; 18F-FDG-PET/CT

Cite this article

AI Xiangyan , LIU Yang , CHENG Fang , ZHAO Futao . A case of primary skeletal muscle peripheral T-cell lymphoma diagnosed by 18F-FDG-PET/CT[J]. Journal of Internal Medicine Concepts & Practice, 2024 , 19(06) : 413 -416 . DOI: 10.16138/j.1673-6087.2024.06.11

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