外科理论与实践 ›› 2022, Vol. 27 ›› Issue (06): 530-533.doi: 10.16139/j.1007-9610.2022.06.010
收稿日期:
2022-09-27
出版日期:
2022-11-25
发布日期:
2023-01-30
通讯作者:
王斌梁,E-mail: 基金资助:
PAN Xiangou, ZHANG Li, HOU Jiazhou, DU Shisuo, ZENG Zhaochong, WANG Binliang()
Received:
2022-09-27
Online:
2022-11-25
Published:
2023-01-30
摘要:
目的: 探讨术前放射治疗(放疗)使切除困难或不可切除腹膜后软组织肉瘤病人转化治疗的效果及对预后的影响。方法: 回顾性分析2017年5月至2022年2月期间,中山医院放疗科44例切除困难或不可手术切除的原发性腹膜后软组织肉瘤病人。采用调强放疗(intensity modulated radiation therapy, IMRT)和螺旋断层放疗(tomothe-rapy, TOMO)技术,观察病人放疗后可切除转化率、预后及术后并发症发生。结果:该44例行放疗,其中IMRT 30例,TOMO 14例。治疗不良反应均为1~2级。放疗后,12例部分缓解,26例病情稳定,6例病情进展。放疗后26例行手术切除,59.1%(26/44)达到转化成可切除的目的。病人1年、3年总生存率分别为93%、72%。结论:术前放疗可有效提高初始切除困难或不可切除原发性腹膜后软组织肉瘤的可切除转化率,且术后生存率较好,不良反应轻度。
中图分类号:
潘向欧, 张莉, 侯佳舟, 杜世锁, 曾昭冲, 王斌梁. 切除困难或不可切除原发性腹膜后软组织肉瘤术前转化放射治疗的研究[J]. 外科理论与实践, 2022, 27(06): 530-533.
PAN Xiangou, ZHANG Li, HOU Jiazhou, DU Shisuo, ZENG Zhaochong, WANG Binliang. Study on preoperative radiotherapy in conversion therapy for patients with primary retroperitoneal soft tissue sarcoma difficult to resect or unresectable[J]. Journal of Surgery Concepts & Practice, 2022, 27(06): 530-533.
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