外科理论与实践

外科理论与实践 ›› 2024, Vol. 29 ›› Issue (06): 493-497.doi: 10.16139/j.1007-9610.2024.06.06

• 论著 • 上一篇    下一篇

下肢静脉曲张病人卵圆孔未闭-右向左分流发生率的研究

岑庆1, 唐明珺2,3, 朱越锋2,4()   

  1. 1.慈溪市人民医院普外科，浙江 宁波 315300
    2.浙江大学医学院附属第四医院血管外科，浙江 义乌 322000
    3.浙江大学国际健康医学研究院，浙江 义乌 322000
    4.浙江大学医学院附属邵逸夫医院血管外科，浙江 杭州 310016
  • 收稿日期:2024-10-14 出版日期:2024-11-25 发布日期:2025-03-17
  • 通讯作者: 朱越锋，E-mail: srrshzyf@zju.edu.cn
  • 基金资助:
    慈溪市公益类科技计划(CN2022003);浙江省中医药科学研究基金(2011ZB079);浙江省医药卫生科技项目(2024KY1184)

The incidence of PFO-RLS in patients with varicose veins of the lower extremities

CEN Qing1, TANG Mingjun2,3, ZHU Yuefeng2,4()   

  1. 1. Department of General Surgery, Cixi People's Hospital, Zhejiang Ningbo 315300， China
    2. Department of Vascular Surgery, the Fourth Affiliated Hospital, Zhejiang University School of Medicine， Zhejiang Yiwu 322000, China
    3. International Institutes of Medicine, Zhejiang University，Zhejiang Yiwu 322000, China
    4. Department of Vascular Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Zhejiang Hangzhou 310016, China
  • Received:2024-10-14 Online:2024-11-25 Published:2025-03-17

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摘要：

目的： 研究评价下肢静脉曲张病人卵圆孔未闭(PFO)-心内右向左分流(RLS)的发生率。方法： 2023年3月至2024年8月期间连续入住慈溪市人民医院下肢静脉曲张病人86例，其中57例同意行泡沫硬化剂治疗，术前行PFO-RLS检查。结果： 57例中，PFO 23例，发生率为40.4%（95% CI: 27.2%~53.5%），心内RLS 22例，发生率为38.6%（95% CI: 25.6%~51.6%）。PFO发生率高于所报道的普通人群26%。所有病人术后均无肺栓塞、卒中等严重并发症发生。结论： 下肢静脉曲张病人PFO-RLS的发生率高于普通人群的预期水平。下肢静脉曲张病人在选择硬化剂治疗的时候需警惕相关神经系统并发症。

关键词: 静脉曲张, 硬化剂治疗, 卵圆孔未闭, 右向左分流

Abstract:

Objective To study and evaluate the incidence of patent foramen ovale（PFO） and intracardiac right-to-left shunt（RLS）in the patients with varicose veins of the lower extremities. Methods From March 2023 to August 2024, 86 consecutive patients with varicose veins of the lower extremities were admitted to Cixi People’s hospital, and 57 of them who agreed to take foam sclerotherapy were selected for PFO-RLS test. Results Of the 57 patients, a total of 23 patients were positive for PFO with an incidence of 40.4% (95% CI: 27.2%-53.5%) and a total of 22 patients were positive for RLS with an incidence of 38.6% (95% CI: 25.6%-51.6%). The incidence of PFO was higher than the reported incidence in the general population, which is 26%. There were no serious complications such as pulmonary embolism or stroke occurred in all patients after surgery. Conclusions The incidence of PFO-RLS in patients with varicose veins of the lower extremities in this study was higher than that of expected in the general population. Patients with lower extremity varicose veins should be aware of the associated neurological complications when choosing sclerotherapy.

Key words: Varicose vein, Sclerotherapy, Patent foramen ovale(PFO), Right-to-left shunt(RLS)

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