Journal of Surgery Concepts & Practice ›› 2022, Vol. 27 ›› Issue (03): 271-275.doi: 10.16139/j.1007-9610.2022.03.018
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LI Rui, LIU Zhuoran, YAN Jiqi(
)
Received:2021-08-12
Online:2022-06-25
Published:2022-08-03
Contact:
YAN Jiqi
E-mail:yanjiqi@aliyun.com
CLC Number:
LI Rui, LIU Zhuoran, YAN Jiqi. Progress of study on medullary thyroid carcinoma with serum calcitonin-negative and large mass[J]. Journal of Surgery Concepts & Practice, 2022, 27(03): 271-275.
| 参考文献 | 性别 | 年龄 （岁） | 肿瘤直 径（cm） | 随访时间 | 预后 | 降钙素（免疫 组织化学） | 术后降 钙素 | 术后癌 胚抗原 | 细针 穿刺 | 转染期 间重排 基因 |
|---|---|---|---|---|---|---|---|---|---|---|
| Samà等[ | 男 | 60 | 3.8 | 10年 | 无复发 | 弱阳性 | 未升高 | 未升高 | / | 阴性 |
| 男 | 53 | 1.2 | 3年 | 无复发 | / | 未升高 | 未升高 | / | 阳性 | |
| 男 | 62 | 4.5 | 1年 | 无复发 | 弱阳性 | 未升高 | 未升高 | / | 阴性 | |
| Sobol等[ | 女 | 82 | 2.0 | 23个月 | 6个月后转移,23个月后死亡 | 阴性 | 未升高 | 未升高 | / | / |
| Redding等[ | 女 | 31 | 4.5 | 43个月 | 无复发 | 强阳性 | 未升高 | 未升高 | 恶性 | / |
| Bockhorn等[ | 女 | 50 | 2.0 | 5年 | 无复发 | 弱阳性 | / | / | / | 阴性 |
| Sand等[ | 女 | 73 | >4.0 | 6周 | 死于肺转移和脑转移 | 弱阳性 | / | / | / | / |
| Giovanella等[ | 女 | 43 | 3.6 | 2年 | 无复发 | 强阳性 | 未升高 | 未升高 | 恶性 | / |
| Dora等[ | 男 | 43 | 1.7 | / | / | 强阳性 | / | / | 恶性 | 阴性 |
| Alapat等[ | 女 | 16 | 3.0 | 20个月 | 无复发 | 强阳性 | 未升高 | 未升高 | MTC | / |
| Frank-Raue等[ | 男 | 70 | 8.0 | 2.25年 | 伴肺转移 | 弱阳性 | 未升高 | 未升高 | / | 阴性 |
| 女 | 50 | 2.0 | 12.5年 | 10年后复发 | 弱阳性 | 未升高 | 升高 | MTC | 阳性 | |
| 男 | 47 | 3.0 | 1.5年 | 无复发 | 强阳性 | 未升高 | 未升高 | / | 阴性 | |
| 女 | 53 | 4.5 | 1.75年 | 伴远处转移 | 强阳性 | 未升高 | 未升高 | MTC | 阳性 | |
| 男 | 45 | 1.8 | 1.75年 | 死于肺转移 | 弱阳性 | 升高 | 未升高 | / | 阳性 | |
| 女 | 45 | 5.5 | 3年 | 死于肺转移 | 强阳性 | 未升高 | 未升高 | / | 阳性 | |
| Brutsaert等[ | 女 | 39 | 2.6 | / | / | 强阳性 | / | / | 恶性 | 阴性 |
| Murphy等[ | 女 | 24 | 3.5 | 3年 | 无复发 | 阴性 | 未升高 | 未升高 | / | 阴性 |
| Jingzhu等[ | 男 | 66 | 7.0 | 2个月 | 死于局部复发 | 强阳性 | / | / | / | / |
| 女 | 65 | 1.48 | 15个月 | 死于肝、脑、肺转移 | 弱阳性 | / | / | / | / | |
| Montgomery等[ | 男 | 45 | 2.3 | / | / | 阴性 | / | / | NET | / |
| [1] |
Viola D, Elisei R. Management of medullary thyroid cancer[J]. Endocrinol Metab Clin North Am, 2019, 48(1):285-301.
doi: 10.1016/j.ecl.2018.11.006 URL |
| [2] |
Wells SA Jr, Asa SL, Dralle H, et al. Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma[J]. Thyroid, 2015, 25(6):567-610.
doi: 10.1089/thy.2014.0335 URL |
| [3] | Ceolin L, Duval MADS, Benini AF, et al. Medullary thyroid carcinoma beyond surgery: advances, challenges, and perspectives[J]. Endocr Relat Cancer, 2019, 26(9):R499-R518. |
| [4] |
Samà MT, Rossetto Giaccherino R, Gallo M, et al. Clinical challenges with calcitonin-negative medullary thyroid carcinoma[J]. J Cancer Res Clin Oncol, 2016, 142(9):2023-2029.
doi: 10.1007/s00432-016-2169-5 URL |
| [5] |
Liu Y, Yuan L, Yang D, et al. Serum calcitonin negative mixed medullary-follicular carcinoma initially diagnosed as medullary thyroid carcinoma by fine-needle aspiration cytology: a case report and review of the literatures[J]. Diagn Cytopathol, 2018, 46(8):690-693.
doi: 10.1002/dc.23924 URL |
| [6] |
Kartal Baykan E, Erdoan M. Basal and pentagastrin-stimulated calcitonin cut-off values in diagnosis of preoperative medullary thyroid cancer[J]. Turk J Med Sci, 2021, 51(2):650-656.
doi: 10.3906/sag-2003-182 pmid: 33128357 |
| [7] |
Filimon S, Payne RJ, Black MJ, et al. Calcitonin secretory index and unsuspected nodal disease in medullary thyroid carcinoma[J]. Endocr Pract, 2018, 24(5):460-467.
doi: 10.4158/EP-2017-0236 pmid: 29847167 |
| [8] | 王宇, 田文, 嵇庆海, 等. 甲状腺髓样癌诊断与治疗中国专家共识(2020版)[J]. 中国实用外科杂志, 2020, 40(9):1012-1020. |
| [9] |
Haddad RI, Nasr C, Bischoff L, et al. NCCN Guidelines Insights: Thyroid Carcinoma, Version 2.2018[J]. J Natl Compr Canc Netw, 2018, 16(12):1429-1440.
doi: 10.6004/jnccn.2018.0089 URL |
| [10] |
Allelein S, Ehlers M, Morneau C, et al. Measurement of basal serum calcitonin for the diagnosis of medullary thyroid cancer[J]. Horm Metab Res, 2018, 50(1):23-28.
doi: 10.1055/s-0043-122237 URL |
| [11] |
Sobol RE, Memoli V, Deftos LJ. Hormone-negative, chromogranin A-positive endocrine tumors[J]. N Engl J Med, 1989, 320(7):444-447.
doi: 10.1056/NEJM198902163200707 URL |
| [12] |
Redding AH, Levine SN, Fowler MR. Normal preoperative calcitonin levels do not always exclude medullary thyroid carcinoma in patients with large palpable thyroid masses[J]. Thyroid, 2000, 10(10):919-922.
pmid: 11081258 |
| [13] |
Bockhorn M, Frilling A, Rewerk S, et al. Lack of eleva-ted serum carcinoembryonic antigen and calcitonin in medullary thyroid carcinoma[J]. Thyroid, 2004, 14(6):468-470.
doi: 10.1089/105072504323150813 URL |
| [14] |
Sand M, Gelos M, Sand D, et al. Serum calcitonin negative medullary thyroid carcinoma[J]. World J Surg Oncol, 2006, 4:97.
doi: 10.1186/1477-7819-4-97 URL |
| [15] |
Giovanella L, Crippa S, Cariani L. Serum calcitonin-negative medullary thyroid carcinoma: role of CgA and CEA as complementary markers[J]. Int J Biol Markers, 2008, 23(2):129-131.
doi: 10.1177/172460080802300212 URL |
| [16] |
Dora JM, Canalli MH, Capp C, et al. Normal perioperative serum calcitonin levels in patients with advanced medullary thyroid carcinoma: case report and review of the literature[J]. Thyroid, 2008, 18(8):895-899.
doi: 10.1089/thy.2007.0231 URL |
| [17] |
Alapat DV, Ain KB, Sloan DA, et al. Disparity between tissue and serum calcitonin and carcinoembryonic antigen in a patient with medullary thyroid carcinoma[J]. Endocrine, 2011, 39(2):148-152.
doi: 10.1007/s12020-010-9433-2 pmid: 21243446 |
| [18] |
Frank-Raue K, Machens A, Leidig-Bruckner G, et al. Prevalence and clinical spectrum of nonsecretory medullary thyroid carcinoma in a series of 839 patients with sporadic medullary thyroid carcinoma[J]. Thyroid, 2013, 23(3):294-300.
doi: 10.1089/thy.2012.0236 pmid: 22946486 |
| [19] |
Brutsaert EF, Gersten AJ, Tassler AB, et al. Medullary thyroid cancer with undetectable serum calcitonin[J]. J Clin Endocrinol Metab, 2015, 100(2):337-341.
doi: 10.1210/jc.2014-3095 pmid: 25490273 |
| [20] |
Zhou Q, Yue S, Cheng Y, et al. Clinical and pathological analysis of 19 cases of medullary thyroid carcinoma without an increase in calcitonin[J]. Exp Toxicol Pathol, 2017, 69(8):575-579.
doi: 10.1016/j.etp.2017.05.003 URL |
| [21] |
Cipri C, Vescini F, Torresan F, et al. An unusual case of medullary thyroid carcinoma and a revision of current li-terature[J]. Endocr Metab Immune Disord Drug Targets, 2019, 19(2):226-229.
doi: 10.2174/1871530319666181220165350 URL |
| [22] | Murphy DC, Johnson SJ, Aspinall S. Calcitonin-negative medullary thyroid carcinoma: the “triple-negative” pheno-type[J]. Ann R Coll Surg Engl, 2020, 102(3):e63-e66. |
| [23] | Jingzhu Z, Xiangqian Z, Ming G, et al. Clinical challenges with calcitonin-negative medullary thyroid carcinoma: three case reports and a review of the literature[J]. Ann R Coll Surg Engl, 2022, 104(3):221-230. |
| [24] |
Kim SJ, Yun HJ, Shin SJ, et al. Serum calcitonin-negative medullary thyroid carcinoma: a case series of 19 patients in a single center[J]. Front Endocrinol (Lausanne), 2021, 12:747704.
doi: 10.3389/fendo.2021.747704 URL |
| [25] |
Montgomery G, Collins L, Coghlin C, et al. Calcitonin negative medullary thyroid cancer in ectopic thyroid tissue: a rare diagnosis in an unusual location[J]. BMJ Case Rep, 2020, 13(8):e236865.
doi: 10.1136/bcr-2020-236865 URL |
| [26] |
Leboeuf R, Langlois MF, Martin M, et al. “Hook effect” in calcitonin immunoradiometric assay in patients with metastatic medullary thyroid carcinoma: case report and review of the literature[J]. J Clin Endocrinol Metab, 2006, 91(2):361-364.
doi: 10.1210/jc.2005-1429 URL |
| [27] |
Fernández-Ferreira R, De la Peña-López IR, Zamudio-Coronado KW, et al. Calcitonin-negative neuroendocrine carcinoma of the thyroid gland: case report and literature review[J]. Case Rep Oncol, 2021, 14(1):112-122.
doi: 10.1159/000510807 pmid: 33776692 |
| [28] |
Leboulleux S, Baudin E, Young J, et al. Gastroenteropancreatic neuroendocrine tumor metastases to the thyroid gland: differential diagnosis with medullary thyroid carcinoma[J]. Eur J Endocrinol, 1999, 140(3):187-191.
doi: 10.1530/eje.0.1400187 pmid: 10216512 |
| [29] |
Konstantinidis A, Stang M, Roman SA, et al. Surgical management of medullary thyroid carcinoma[J]. Updates Surg, 2017, 69(2):151-160.
doi: 10.1007/s13304-017-0443-y pmid: 28409442 |
| [30] | Hassan A, Siddique M, Riaz S, et al. Medullary thyroid carcinoma: prognostic variables and tumour markers affecting survival[J]. J Ayub Med Coll Abbottabad, 2018, 30(4):S627-S632. |
| [31] |
Parmer M, Milan S, Torabi A. Calcitonin-negative neuroendocrine tumor of the thyroid[J]. Int J Surg Pathol, 2017, 25(2):191-194.
doi: 10.1177/1066896916670989 pmid: 27658647 |
| [32] |
Giovanella L, Garo ML, Ceriani L, et al. Procalcitonin as an alternative tumor marker of medullary thyroid carcinoma[J]. J Clin Endocrinol Metab, 2021, 106(12):3634-3643.
doi: 10.1210/clinem/dgab564 pmid: 34382653 |
| [33] |
Karagiannis AK, Girio-Fragkoulakis C, Nakouti T. Procalcitonin: a new biomarker for medullary thyroid cancer? a systematic review[J]. Anticancer Res, 2016, 36(8):3803-3810.
pmid: 27466480 |
| [34] |
Vargas CVF, Ceolin L, Scheffel RS, et al. The tissue expression pattern of CA 19.9 is associated with oncological features in medullary thyroid carcinoma[J]. Endocrine, 2020, 70(3):544-551.
doi: 10.1007/s12020-020-02377-3 URL |
| [35] |
Elisei R, Lorusso L, Piaggi P, et al. Elevated level of serum carbohydrate antigen 19.9 as predictor of mortality in patients with advanced medullary thyroid cancer[J]. Eur J Endocrinol, 2015, 173(3):297-304.
doi: 10.1530/EJE-15-0304 URL |
| [36] |
Liu MJ, Liu ZF, Hou YY, et al. Ultrasonographic characteristics of medullary thyroid carcinoma: a comparison with papillary thyroid carcinoma[J]. Oncotarget, 2017, 8(16):27520-27528.
doi: 10.18632/oncotarget.15897 URL |
| [37] | Tripathy S, Aggrawal S, Subudhi K, et al. Calcitonin-negative neuroendocrine tumor of the thyroid on 68Ga DOTANOC PET-CT[J]. Clin Nucl Med, 2019, 44(9):e546-e547. |
| [38] |
Naswa N, Sharma P, Suman Kc S, et al. Prospective evaluation of 68Ga-DOTA-NOC PET-CT in patients with recurrent medullary thyroid carcinoma: comparison with 18F-FDG PET-CT[J]. Nucl Med Commun, 2012, 33(7):766-774.
doi: 10.1097/MNM.0b013e3283541157 URL |
| [39] |
Trimboli P, Giovanella L, Crescenzi A, et al. Medullary thyroid cancer diagnosis: an appraisal[J]. Head Neck, 2014, 36(8):1216-1223.
doi: 10.1002/hed.23449 URL |
| [40] |
Trimboli P, Cremonini N, Ceriani L, et al. Calcitonin measurement in aspiration needle washout fluids has higher sensitivity than cytology in detecting medullary thyroid cancer: a retrospective multicentre study[J]. Clin Endocrinol (Oxf), 2014, 80(1):135-140.
doi: 10.1111/cen.12234 URL |
| [41] |
Salvatore D, Santoro M, Schlumberger M. The importance of the RET gene in thyroid cancer and therapeutic implications[J]. Nat Rev Endocrinol, 2021, 17(5):296-306.
doi: 10.1038/s41574-021-00470-9 pmid: 33603219 |
| [42] |
Thomas CM, Asa SL, Ezzat S, et al. Diagnosis and pathologic characteristics of medullary thyroid carcinoma-review of current guidelines[J]. Curr Oncol, 2019, 26(5):338-344.
doi: 10.3747/co.26.5539 pmid: 31708652 |
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