Role of biliary microbiota in the pathogenesis of bile duct stones: latest research progress

doi:10.16139/j.1007-9610.2024.06.15

Abstract

Abstract:

The pathogenesis of bile duct stones (BDS) remains intricate and has not been fully elucidated to date. Emerging research has highlighted the biliary microbiota as a significant contributor to BDS. The diversity within the biliary microbiota correlates with stone formation, while bacterial metabolites and their self-protection mechanisms also exert pivotal roles in this process. Advanced technologies, such as high-throughput sequencing, offer fresh perspectives for in-depth exploration, and hold promise for novel strategies in the prevention and treatment of biliary tract diseases. This article comprehensively reviewed the recent advancements in research concerning the relationship and mechanisms between BDS and the biliary microbiota.

Key words: Bile duct stones(BDS), Biliary microbiota, High-throughput sequencing

CLC Number:

R657.42

WANG Xiaoning, WU Xiaodong, WU Shuodong, HAN Jinyan. Role of biliary microbiota in the pathogenesis of bile duct stones: latest research progress[J]. Journal of Surgery Concepts & Practice, 2024, 29(06): 544-548.

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