Abstract: Objective To compare the efficacy of laparoscopic complete mesocolic excision (CME) for right colon cancer with open CME. Methods The clinical data of the patients with right colon cancer in our department from January 2010 to December 2014 was retrospectively analyzed. There were 102 patients with laparoscopic CME as laparoscopic group and 116 patients with open CME as open group. Peri-operative outcomes and survival were compared between two groups. Results The baseline information was not significantly different between two groups (P> 0.05). Compared with open group, the patients in laparoscopic group had longer operating time [(155.20± 4.17) min vs (140.10± 4.00) min, P=0.009 6], but less bleeding [(102.60± 7.37) mL vs(145.90± 12.23) mL, P=0.003 7], more retrieved lymph nodes [(12.17± 0.39) vs(10.78± 0.42), P=0.016 8], faster recovery course including shorter time to liquid diet [(2.91± 0.47) day vs (3.62± 0.41) day, P=0.034] and shorter postoperative hospital stay [(10.59± 0.57) day vs (14.13± 0.52) day, P=0.041]. No significant difference was observed in the postoperative complications between two groups. The period of follow-up had no significant difference between two groups [(38.83± 1.73) month vs (30.74± 1.60) month, P> 0.05]. Three-year survival rate of the patients in laparoscopic group was significantly higher than that in open group (89.81% vs 82.22%, P=0.048 2). Conclusions Laparoscopic CME provides the patients of right colon cancer with faster recovery and better overall survival.

Key words: Laparoscopic surgery, Open surgery, Right colon cancer, Complete mesocolic excision