Abstract: Objective: To explore the feasibility of laparoscopic-assisted distal gastrectomy with D2 lymphadenectomy for advanced gastric cancer in primary hospital and examine the outcomes compared to open surgery. Methods: The patients with advanced gastric cancer were divided into laparoscopic group and open group each 40 cases in our hospital from January 2016 to March 2018. Retrospective analysis was performed for short-term clinical results. Results: The operating time, blood loss, first flatus time, out of bed time and first feeding time in laparoscopic group were(183.71±16.08) min, (64.02±10.69) mL, (3.08±0.61) d, (2.88±0.70) d, (3.10±0.71) d, respectively with the statistical difference when compared to those in open group (P<0.05). The retrieved lymph node and the length of distal and proximal resection margins away from the cancer were (30.70±8.84), (4.73±1.16) cm and (7.10±1.14) cm without significant difference statistically between two groups(P>0.05). The rate of incision infection and pulmonary infection in open group was higher than that in laparoscopic group(P<0.05). However, the difference between two groups was not present in the anastomotic bleeding and leakage and gastroparalysis (P>0.05). Conclusion: Laparoscopic-assisted gastrectomy has similar curative effect compared to open surgery with the advantages of less blood loss and quicker recovery.

Key words: Laparoscopic-assisted surgery, D2 lymphadenectomy, Advanced gastric cancer