Abstract: Objective To investigate the perioperative efficacy of 3D laparoscopic D2 radical gastrectomy in the treatment of advanced gastric cancer. Methods We analyze retrospectively 181 cases with advanced gastric cancer undergoing D2 radical gastrectomy in our department from January 2016 to December 2018 including 87 cases of 3D laparoscopic gastrectomy (3D group) and 94 cases of open gastrectomy (open group). The perioperative data were compared between two groups. Results There was no case in 3D group conversion to open. R0 dissection was gotten all in this study. No perio-perative mortality was found. There was no significant difference in operative time, postoperative hospital stay and postope-rative complications between two groups (P>0.05). The intraoperative blood loss in 3D group (155.06±144.95) mL was significantly less than that in open group (214.47±220.58) mL (P=0.035). Postoperative pass gas time, the time in taking li-quid food and semi-liquid food were all earlier in 3D group than those in open group significantly (P=0.004, P<0.05). No significant difference was present in lymph node dissection between two groups (P>0.05). Conclusions 3D laparoscopic D2 radical gastrectomy could be a safe and feasible surgical type for advanced gastric cancer with quicker recovery and minimal injury.

Key words: Advanced gastric cancer, 3D laparoscopic D2 radical gastrectomy, Perioperative efficacy