Journal of Surgery Concepts & Practice >

2023 , Vol. 28 >Issue 06: 501 - 506

DOI: https://doi.org/10.16139/j.1007-9610.2023.06.03

Experts forum

Update of pathology in medullary thyroid carcinoma

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  • 1. Department of Pathology, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China
    2. Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Izumi Osaka 594-0073, Japan

Received date: 2023-11-06

  Online published: 2024-03-04

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Abstract

Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy, which is more aggressive with high metastasis and recurrence rate. Surgical treatment is the preferred treatment option for MTC. Targeted therapy and immunotherapy have gradually become new treatment strategy for MTC. The pathology of MTC was updated in the 5th edition WHO classification of endocrine and neuroendocrine tumor in 2022. This review summarized the update of MTC pathology focusing on the histologic grading schemes, gene screening and genetic counseling.

Key words： Medullary thyroid carcinoma; Histologic grading scheme; Genetic screening; Genetic counseling

Cite this article

LIU Zhiyan, YU Yaling, KAKUDO Kennichi . Update of pathology in medullary thyroid carcinoma[J]. Journal of Surgery Concepts & Practice, 2023 , 28(06) : 501 -506 . DOI: 10.16139/j.1007-9610.2023.06.03

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