组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2012, Vol. 8 ›› Issue (2): 114-116.doi: 10.3969/j.issn.1673-0364.2012.02.015

• 论著 • 上一篇    下一篇

光动力学治疗皮肤相关疾病的研究进展

李昕，李伟   

  1. 上海交通大学医学院附属第九人民医院整复外科
  • 发布日期:2020-07-23

Photodynamic Therapy in the Treatment of Skin Disorders

LI Xin,LI Wei   

  1. Department of Plastic and Reconstructive Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China.
  • Published:2020-07-23
  • Contact: 国家自然科学基金项目　　（81071565）

摘要： 光动力学治疗是通过光照,激活光敏剂,产生光化学反应,进而对治疗组织产生杀伤作用。已被广泛应用于治疗各类上皮性肿瘤。近年来,在非肿瘤性疾病的治疗中也被证实具有良好治疗。本文就光动力学治疗的研究进展以及在皮肤相关疾病中的应用进行综述。

关键词: 光动力学治疗, 光敏剂, 5-氨基酮戊酸, 皮肤疾病

Abstract: Photodynamic therapy interacted with light by activating photosensitive agents to produce singlet oxygen resulting in targeted cell death.It has been widely used in the treatment of various epithelial tumors.Recently,it has been also proved to be efficient in many non-malignant diseases.The recent progress on photodynamic therapy and its application in malignant and non-malignant skin disorders will be reviewed in this article.

Key words: Photodynamic therapy, Photosensitizer, 5-aminolevulinic acid, Skin disorder

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