组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2017, Vol. 13 ›› Issue (3): 172-174.doi: 10.3969/j.issn.1673-0364.2017.03.015

• 综述 • 上一篇    下一篇

长链非编码RNA与颅颌面发育及畸形的相关性研究进展

孟小辉，宋涛   

  1. 中国医学科学院整形外科医院
  • 发布日期:2020-07-23

Research Progress of Long Noncoding RNAs in Craniomaxillofacial Development and Deformities

MENG Xiaohui   

  • Published:2020-07-23

摘要： 先天性颅颌面畸形是临床较多见的生长发育缺陷.长链非编码RNA(Long non-coding RNA,lncRNA)是指长度大于200个核苷酸,无法编码蛋白的RNA.近年来,越来越多的研究表明,lncRNA在颅颌面的生长发育进程中有着重要的作用.本文对lncRNA与颅颌面发育及畸形的相关性研究进展进行综述.

关键词: 长链非编码RNA, 颅颌面发育, 颅颌面畸形

Abstract: Congenital craniomaxillofacial deformities are common human growth and development defects. A long non-coding RNA (lncRNA) is an RNA longer than 200 nucleotides that are not predicted to be translated to a functional protein product. Recently, an increasing number of studies have shown that lncRNA have a critical role in processes of craniomaxillofacial development. In this paper, the research progress of long non-coding RNAs in craniomaxillofacial development and deformities was reviewed.

Key words: Long non-coding RNA, Craniomaxillofacial development, Craniomaxillofacial deformity

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