组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2019, Vol. 15 ›› Issue (5): 359-361.doi: 10.3969/j.issn.1673-0364.2019.05.013

• 综述 • 上一篇    下一篇

利用生物三维打印技术修复软骨损伤的研究进展

韩倩倩，王苗苗，史建峰，王迎，连环，王蕊，李静莉，王春仁   

  1. 中国食品药品检定研究院
  • 收稿日期:2019-08-19 修回日期:2019-09-04 出版日期:2019-10-20 发布日期:2019-10-20
  • 作者简介:共同第一作者:韩倩倩,王苗苗;李静莉(E-mail:jinglil996@sina.com);王春仁(Email:chunrenwang@263.net)。

Research Progress of Bio-3D Printing for the Repair of Cartilage Damage

HAN Qianqian,WANG Miaomiao,SHI Jianfeng,WANG Ying,LIAN Huan,WANG Rui,LI Jingli,WANG Chunren   

  1. Medical Device Control, National Institute of Food and Drug Control,CFDA
  • Received:2019-08-19 Revised:2019-09-04 Online:2019-10-20 Published:2019-10-20
  • Contact: 国家重点研发计划(2016YFC1103202)

摘要： 软骨组织因缺乏血供,自我修复能力极其有限,导致软骨损伤后难以再生修复。生物三维打印技术突破了传统组织工程技术仿生功能设计的局限性,可一体化成型并精确制备复杂结构,还可以将细胞打印于支架材料中,构建适合细胞生存的微环境,在软骨修复和再生领域具有优势。本文对生物三维打印技术修复软骨的研究进展进行综述。

关键词: 生物材料, 软骨损伤, 生物三维打印

Abstract: The self-repairing ability of cartilage tissue is limited due to the lack of blood supply. This makes it difficult to regenerate and repair after cartilage injury. The bio-3 d printing technology breaks through the limitations of bionic function design of traditional tissue engineering technology, and can be integrated into molding and accurately prepare complex structures. Moreover, it can also print cells into scaffold materials to construct microenvironment suitable for cell survival, which has advantages in the field of cartilage repair and regeneration. In this paper, the research progress of the cartilage repair using bio-3 D printing was reviewed.

Key words: Biomaterials, Cartilage damage, Bio-3D printing

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